Responses of the splanchnic circulation to ischaemia.

Marston, Adrian

doi:10.1136/jcp.s3-11.1.59

Cited by 26 publications

(17 citation statements)

References 21 publications

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“…15,16 The response to this intestinal ischemia is the release of serotonin, thus stimulating the CTZ. 17 These two studies provide some evidence that the use of supplemental oxygen in the perioperative period may reduce PONV by ameliorating intestinal ischemia, thus reducing the release of serotonin.…”

Section: Supplemental Oxygenmentioning

confidence: 97%

Therapeutic Modalities for the Prophylactic Management of Postoperative Nausea and Vomiting

Couture¹,

Maye²,

O’Brien³

et al. 2006

Journal of PeriAnesthesia Nursing

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Section: Supplemental Oxygenmentioning

confidence: 97%

Therapeutic Modalities for the Prophylactic Management of Postoperative Nausea and Vomiting

Couture¹,

Maye²,

O’Brien³

et al. 2006

Journal of PeriAnesthesia Nursing

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“…Sehr hohe inspiratorische O 2 −Konzentrationen (nahe 100 %) kön− nen lungentoxisch sein [41]. Allerdings entwickelt sich eine sol− che Toxizität erst nach tagelanger Exposition [41].…”

Section: Mögliche Nachteile Einer Hohen Fiounclassified

“…Allerdings entwickelt sich eine sol− che Toxizität erst nach tagelanger Exposition [41]. Die kurzzeiti− ge perioperative Exposition mit hohen inspiratorischen O 2 −Kon− zentrationen erscheint dagegen unbedenklich und verbessert möglicherweise sogar die pulmonale Infektabwehr [41].…”

Section: Mögliche Nachteile Einer Hohen Fiounclassified

Routine Use of High Inspired Oxygen Concentration - Pro

Danzeisen

Priebe²

2005

Anasthesiol Intensivmed Notfal

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Seit der Erstbeschreibung durch den Chemiker Joseph Priestley 1775 und den Apotheker Carl Wilhelm Scheele 1777 wurden dem Sauerstoff viele therapeutische Eigenschaften zugespro− chen [1, 2]. Er wurde als ¹Allheilmittel" propagiert, und selbst die intravenöse Gabe wurde als eine der ¹Chief methods for the therapeutic employement of oxygen" angesehen [3]. Zwar wis− sen wir heute weit mehr über Wirkweise und Applikationsfor− men von Sauerstoff, aber gerade in der Anästhesie gehen nach wie vor die Meinungen über die angemessene intraoperative inspiratorische Sauerstoffkonzentration auseinander. Unserer Überzeugung nach spricht jedoch weit mehr für als gegen die routinemäßige intraoperative Verwendung hoher inspiratori− scher Sauerstoffkonzentrationen (FiO 2 ).

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“…The major arteries supplying the splanchnic organs are the celiac artery, the superior mesenteric artery and inferior mesenteric artery, which branch off from the aorta and give rise to smaller arteries that anastomose extensively. Splanchnic blood is drained to the liver via the portal vein, and flows from the liver to the inferior vena cava via the hepatic veins [101,127]. Since the splanchnic circulation receives about 25% of the cardiac output, alterations in the splanchnic circulation may have important clinical consequences.…”

Section: Introductionmentioning

confidence: 99%

Purinergic receptors in the splanchnic circulation

Morato

Sousa

Albino‐Teixeira

2008

Purinergic Signalling

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There is considerable evidence that purines are vasoactive molecules involved in the regulation of blood flow. Adenosine is a well known vasodilator that also acts as a modulator of the response to other vasoactive substances. Adenosine exerts its effects by interacting with adenosine receptors. These are metabotropic G-protein coupled receptors and include four subtypes, A 1 , A 2A , A 2B and A 3 . Adenosine triphosphate (ATP) is a co-transmitter in vascular neuroeffector junctions and is known to activate two distinct types of P2 receptors, P2X (ionotropic) and P2Y (metabotropic). ATP can exert either vasoconstrictive or vasorelaxant effects, depending on the P2 receptor subtype involved. Splanchnic vascular beds are of particular interest, as they receive a large fraction of the cardiac output. This review focus on purinergic receptors role in the splanchnic vasomotor control. Here, we give an overview on the distribution and diversity of effects of purinergic receptors in splanchnic vessels. Pre-and post-junctional receptormediated responses are summarized. Attention is also given to the interactions between purinergic receptors and other receptors in the splanchnic circulation.

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Responses of the splanchnic circulation to ischaemia.

Cited by 26 publications

References 21 publications

Therapeutic Modalities for the Prophylactic Management of Postoperative Nausea and Vomiting

Therapeutic Modalities for the Prophylactic Management of Postoperative Nausea and Vomiting

Routine Use of High Inspired Oxygen Concentration - Pro

Purinergic receptors in the splanchnic circulation

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