Response Surface Methodology

Sarabia, L.A.; Ortiz, M.C.

doi:10.1016/b978-044452701-1.00083-1

Cited by 142 publications

(100 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Likewise, the coefficient of multiple determination of the polynomial model termed R 2 , indicates that more than 98% of the variability in the response could be explained by the second-order polynomial predicted equation given above. In this respect, the validity of the model has been established by comparing the obtained results at the four check points (experiments [17][18][19][20] with the predicted values (Table 2). These results seem to confirm the validity of the model.…”

Section: Model Equationmentioning

confidence: 99%

“…The optimization of the experimental conditions of a propyl gallate synthesis was achieved by using the Response Surface Methodology (RSM) [19]. In this work, a quadratic polynomial model was set up in order to study the empirical relationship between conversion yield and three controlled factors namely: X 1 , temperature; X 2 , amount of immobilized lipase and X 3 , 1-propanol/gallic acid molar ratio.…”

Section: Experimental Designmentioning

confidence: 99%

See 1 more Smart Citation

Enzymatic propyl gallate synthesis in solvent-free system: Optimization by response surface methodology

Bouaziz¹,

Horchani²,

Salem³

et al. 2010

Journal of Molecular Catalysis B: Enzymatic

View full text Add to dashboard Cite

a b s t r a c tThe ability of a non-commercial immobilized Staphylococcus xylosus lipase to catalyze the esterification of propanol with gallic acid was investigated and the antioxidant as well as the antimicrobial activities of the ester formed were evaluated. The response surface methodology, based on a three variables Box-Behnken design (reaction temperature, enzyme amount and 1-propanol/gallic acid molar ratio), was used to optimize the experimental conditions of propylgallate synthesis. The maximum conversion yield (90% ±3.5) was obtained by using 400 IU of immobilized lipase and a propanol/gallic acid at a molar ratio of 160 at 52 • C. The obtained ester was characterized by spectroscopic methods, NMR and FTIR. The antioxidant activity of propyl gallate was evaluated and compared to the synthetic classical antioxidants, BHA and ascorbic acid, taken as references. In addition, the antimicrobial activity of the propyl gallate was tested against S. xylosus, Escherchia coli and Staphylococcus aureus using disc diffusion and macrodilution methods. Our results show that the synthesized propyl gallate ester presents a higher antioxidant and antimicrobial power than the parent gallic acid as well as the synthetic classical antioxidants.

show abstract

Section: Model Equationmentioning

confidence: 99%

Section: Experimental Designmentioning

confidence: 99%

Enzymatic propyl gallate synthesis in solvent-free system: Optimization by response surface methodology

Bouaziz¹,

Horchani²,

Salem³

et al. 2010

Journal of Molecular Catalysis B: Enzymatic

View full text Add to dashboard Cite

show abstract

“…CCD was first studied by Box and Wilson in 1951 and is still the most popular design for experiments. CCD has three groups of design points that are codified to summarize the data and ease of statistical calculations: (i) two-level factorial design points (2 k ), consists of all possible combinations of the +1 and −1 codified levels of the factors, (ii) axial or star points (2k) codified as (α = (2 k ) 1/4 ) have all of the factors set to 0, the midpoint, except one factor, which has the value ± α., and (iii) center points are points with all levels set to coded level 0 [178].…”

Section: Simulating Testing Practice: Rsm Modelmentioning

confidence: 99%

Making Fe0-Based Filters a Universal Solution for Safe Drinking Water Provision

et al. 2017

View full text Add to dashboard Cite

Metallic iron (Fe 0 )-based filtration systems have the potential to significantly contribute to the achievement of the United Nations (UN) Sustainable Development Goals (SDGs) of substantially improving the human condition by 2030 through the provision of clean water. Recent knowledge on Fe 0 -based safe drinking water filters is addressed herein. They are categorized into two types: Household and community filters. Design criteria are recalled and operational details are given. Scientists are invited to co-develop knowledge enabling the exploitation of the great potential of Fe 0 filters for sustainable safe drinking water provision (and sanitation).

show abstract

“…Central composite, Dohelert and Box Behnken designs are widely used and allow the researcher to choose the most suitable one for approaching the optimization problem [13][14][15][16][17] . Struvite (MgNH 4 PO 4 · 6H 2 O) precipitation from industrial wastewater streams occurs under certain environmental conditions of pH, alkalinity, temperature, phosphorus, ammonium and magnesium concentrations which vary with water source and interfering ions presence.…”

Section: Introductionmentioning

confidence: 99%

Modeling and Optimization of Phosphate Recovery from Industrial Wastewater and Precipitation of Solid Fertilizer using Experimental Design Methodology

Shalaby¹

2015

Chem.Biochem.Eng.Q.

View full text Add to dashboard Cite

Response Surface Methodology

Cited by 142 publications

References 26 publications

Enzymatic propyl gallate synthesis in solvent-free system: Optimization by response surface methodology

Enzymatic propyl gallate synthesis in solvent-free system: Optimization by response surface methodology

Making Fe0-Based Filters a Universal Solution for Safe Drinking Water Provision

Modeling and Optimization of Phosphate Recovery from Industrial Wastewater and Precipitation of Solid Fertilizer using Experimental Design Methodology

Contact Info

Product

Resources

About