Respiratory Variables and Exposure-Effect Relationships in Isocyanate-Exposed Workers

Dl, Holness; Broder, I.; Pn, Corey; Booth, N. E.; Mozzon, D.; Ma, Nazar; Guirguis, S.

doi:10.1097/00043764-198406000-00018

Cited by 25 publications

(16 citation statements)

References 20 publications

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“…Other studies have observed that chronic cough was the most consistent symptom related to wood dust exposure (Holness et al 1985;Shamssain 1992;Norrish et al 1992;Schlünssen et al 2002;Douwes et al 2001;Whitehead et al 1982) but none of those studies has measured the airborne fungi exposure. A correlation between dust and fungi level could be suspected but was not demonstrated in our study.…”

Section: Discussionmentioning

confidence: 99%

Effects of bioaerosol exposure on work-related symptoms among Swiss sawmill workers

Rusca¹,

Charrière

Droz

et al. 2007

Int Arch Occup Environ Health

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Objective Exposure to bioaerosols in the occupational environment of sawmills could be associated with a wide range of health eVects, in particular respiratory impairment, allergy and organic dust toxic syndrome. The objective of the study was to assess the frequency of medical respiratory and general symptoms and their relation to bioaerosol exposure. Method Twelve sawmills in the French part of Switzerland were investigated and the relationship between levels of bioaerosols (wood dust, airborne bacteria, airborne fungi and endotoxins), medical symptoms and impaired lung function was explored. A health questionnaire was distributed to 111 sawmill workers. Results The concentration of airborne fungi exceeded the limit recommended by the Swiss National Insurance (SUVA) in the twelve sawmills. This elevated fungi level signiWcantly inXuenced the occurrence of bronchial syndrome (deWned by cough and expectorations). No other health eVects (irritations or respiratory eVects) could be associated to the measured exposures. We observed that junior workers showed signiWcantly more irritation syndrome (deWned by itching/running nose, snoring and itching/red eyes) than senior workers. Lung function tests were not inXuenced by bioaerosol levels nor dust exposure levels. ConclusionResults suggest that occupational exposure to wood dust in a Swiss sawmill does not promote a clinically relevant decline in lung function. However, the occurrence of bronchial syndrome is strongly inXuenced by airborne fungi levels.

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Section: Discussionmentioning

confidence: 99%

Effects of bioaerosol exposure on work-related symptoms among Swiss sawmill workers

Rusca¹,

Charrière

Droz

et al. 2007

Int Arch Occup Environ Health

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“…However, Ahman et al [22] looked for inflammatory markers in nasal fluid, and found inflammatory effects associated with wood dust on the nasal mucosa. The variability observed in the prevalence of clinical between subjects among the carpenters could be explained by the fact that this prevalence would be linked to concentrations of dust, the hardness of the wood, their nature, handling method and the nature of the associated chemicals [23,24]. unlike Laraqui et al [5], who found a significant difference between the prevalence between two categories.…”

Section: Discussion Prevalence Of Respiratory Symptomsmentioning

confidence: 99%

Respiratory Symptoms and Pulmonary Function tests among Informal Sector Workers Exposed to Wood Dust in Douala, Cameroon

Nde¹,

Mbatchou²

2015

J Allergy Ther

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“…Among workers exposed to pine and medium density fibreboard, SHAMSSAIN et al [2] revealed a dose-response relationship between duration of employment and decreased FVC and FEV1/FVC. HOLNESS et al [22] presented a dose-response relationship between decreased FEV1 and an exposure time index for furniture workers exposed to medium density fibreboard. In a study of furniture workers exposed to softwoods, WHITEHEAD et al [23] reported a dose effect of cumulative exposure and a reduced ratio of FEV1/FVC to both hardwood and softwood.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal lung function decline and wood dust exposure in the furniture industry

Jacobsen¹,

Schlünssen²,

Schaumburg³

et al. 2008

European Respiratory Journal

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The aim of the present study was to investigate the relationship between change in lung function and cumulative exposure to wood dust.In total, 1,112 woodworkers (927 males, 185 females) and 235 reference workers (104 males, 185 females) participated in a 6-yr longitudinal study. Forced expiratory volume in one second (FEV1), forced vital capacity (FVC), height and weight were measured, and questionnaire data on respiratory symptoms, wood dust exposure and smoking habits were collected. Cumulative inhalable wood dust exposure was assessed using a study-specific job exposure matrix and exposure time.The median (range) for cumulative wood dust exposure was 3.75 (0-7.55) mg?year?m -3. A doseresponse relationship between cumulative wood dust exposure and percent annual decrease in FEV1 was suggested for female workers. This was confirmed in a linear regression model adjusted for confounders, including smoking, height and age. An additional difference of -14.50 mL?yr -1 and -27.97 mL?yr , respectively, compared with non-/low-exposed females. For females, a positive trend between wood dust exposure and the cumulative incidence proportion of FEV1/FVC ,70% was suggested.In conclusion, in the present low-exposed cohort, female woodworkers had an accelerated decline in lung function, which may be clinically relevant.

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Respiratory Variables and Exposure-Effect Relationships in Isocyanate-Exposed Workers

Cited by 25 publications

References 20 publications

Effects of bioaerosol exposure on work-related symptoms among Swiss sawmill workers

Effects of bioaerosol exposure on work-related symptoms among Swiss sawmill workers

Respiratory Symptoms and Pulmonary Function tests among Informal Sector Workers Exposed to Wood Dust in Douala, Cameroon

Longitudinal lung function decline and wood dust exposure in the furniture industry

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