Respiratory health risk assessment of children living close to industrial areas in Indonesia

Salami, Indah Rachmatiah Siti; As, Zulfikar Ali; Marselina, Mariana; Roosmini, Dwina

doi:10.1515/reveh-2014-0034

Cited by 7 publications

(7 citation statements)

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“…Premature mortality such as stroke, ischemic heart disease, diabetes and COPD, was more frequent in all provinces in Kalimantan than in Indonesia overall [16]. One plausible explanation for this is that Kalimantan has a number of industrial areas which may affect air quality [37,38].…”

Section: Plos Onementioning

confidence: 99%

Tobacco smoking and risk of all-cause mortality in Indonesia

2020

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Tobacco is well known as a risk factor for early morbidity and mortality worldwide. However, the relative risk of mortality and the effects of smoking vary among the countries. Indonesia, as one of the world’s largest market for smoking tobacco, is significantly affected by tobacco-related illness. Previous research has shown that smoking causes several diseases, including stroke, neoplasm and coronary heart disease. There has to date been no research on the hazard risk of smoking for all-cause mortality in Indonesia. This study aimed to identify the association between smoking and all-cause mortality rates in Indonesia. Information from a total of 3,353 respondents aged 40 years and older was collected in this study. The data were taken from the Indonesian Family Life Survey (IFLS) Wave 4 (2007) to collect personal information and determine smoking status and from Wave 5 (2015) to collect information about deaths. Current smokers make up 40.3% of Indonesia’s population. Current smokers were more likely to have a higher risk of all-cause death (hazard ratio = 1.48, 95% confidence interval = 1.11 to 1.98) than non-current smokers. The number of smokers in Indonesia remains high and is expected to increase gradually every year. A firm government policy is needed to reduce the number of smokers in Indonesia which would automatically reduce the health problem of smoking-related illness in the future.

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Section: Plos Onementioning

confidence: 99%

Tobacco smoking and risk of all-cause mortality in Indonesia

2020

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“…The Framingham Heart Study (42) found negative associations with FEV 1 and FVC (each 2 μg/m³ increase in PM 2.5 was associated with a 13.5 mL lower FEV 1 and 18.7 mL lower FVC), but not To the best of our knowledge, our study is the first to use exposure dose in examining the effects of long-term ambient PM 2.5 exposure on children's lung function. We are aware of only one previous study that used predicted average daily intake (ADD) of respirable PM (44), which found that the risk for having impaired respiratory function was 1.3 times greater in children with higher ADD due to living in industrial areas than those in the control group. In the present study, we only found significant associations of lung function with estimated ADD of PM 2.5 but not with concentrations of PM 2.5 , after adjusting for individual information, indoor air pollution factors, and nutrition and exercise variables in the models.…”

Section: Discussionmentioning

confidence: 99%

Long-term exposure to PM2.5 and Children’s lung function: a dose-based association analysis

Cao

Duan

et al. 2020

J Thorac Dis

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Background: The current literature is still not consist regarding the effect of long-term exposure to PM2.5 and children's lung function, partly due to inadequate or inaccurate exposure assessment. In this study, we aim to investigate the associations between long-term exposure to PM2.5, estimated as average daily dose (ADD), and lung function in school-age children. Methods: We recruited 684 participants of 7-12 years old from the city of Lanzhou located in northwestern China. Participants underwent spirometric tests for lung function and responded to a questionnaire survey.Detailed information about individual air exposure and personal information were collected, including length of school hours, home address, age, gender, etc. Combining the spatial distribution of PM2.5 concentrations in the past 5 years and individual time-activity data, we estimated annual ADD for 5 years preceding the lung function tests and 5-year average ADD, respectively. We used multiple linear regression models to examine the associations between ADD values and lung function, controlling for a range of individual-level covariates. Results: The 5-year average ADD among all the participants was 50.5 μg/kg-d, with higher values estimated for children living in the urban area than the suburban area, for boys than girls, and for children whose parents received a lower education attainment. We found that a 1 μg/kg-d increment in ADD of PM2.5 was associated with a 10.49 mL (95% CI: −20.47, −0.50) decrease in forced vital capacity (FVC) and a 7.68 mL (95% CI: −15.80, −0.44) decrease in forced exploratory volume in 1 second (FEV 1 ). Among the annual ADDs estimated for the preceding 5 years, the immediate past year prior to lung function measurement had the greatest effect on lung function. The effect was greater in girls than in boys. We found no associations between annual exposure of PM2.5 (instead of ADD) and lung function when defined concentration was used as an exposure variable. Conclusions: Long-term PM2.5 exposure, when estimated as exposure dose averaged over a year or longer, was associated with statistically significant reductions in FVC and FEV1 in children of elementaryschool age. Future studies may consider the use of individual-level dose estimates (as opposed to exposure concentrations) to improve the dose-response assessment.

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“…Compared to other industries, the coal and oil shale industries are reported to be the most impactful. A study in Indonesia's coal industrial areas shows that the concentration of PM2.5 is three times higher than in the non-industrialized region, impairing the lung function of more than 68% of children living in that area [3]. At the same time, research in Estonia's oil shale industry areas evaluates the fractional exhaled nitric oxide (FeNO), a marker of lung inflammation, of schoolchildren exposed to hydrocarbons like formaldehyde and benzene.…”

Section: Neurological Development Disordersmentioning

confidence: 99%

“…Juveniles are especially susceptible to these detriments. Multiple types of research have shown that juveniles living near industrial areas have a higher risk of developing neurological development disorders, respiratory problems, cardiovascular diseases, and infant mortality [1][2][3][4][5]. There is also a relationship between industrial pollution and pediatric cancers [6].…”

Section: Introductionmentioning

confidence: 99%

Industrial pollutions on the health effects of infants, children, and adolescents: A systematic review

Wang

2023

TNS

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Industrial pollution is considered especially harmful to juveniles health. This paper analyzes the effect of common pollutants, including particulate matter, nitrogen oxides, persistent organic pollutants, and heavy metals, on three different types of diseases. It can be concluded that particulate matter, nitrogen oxide, and POPs are significantly associated with neurodevelopmental deficiencies in infants. Endocrine-disrupting effects and neuroinflammation are considered the leading causes, but the specific mechanisms remain questioned. Pollutants from heavy industries have a higher potential to cause childrens respiratory diseases, and residency within 4 km of the industry is especially hazardous. Biomarkers VEGF and urinary 8-OHdG reflect a high glutathione-related oxidative burden for exposure to toxic metals attached to particulate matter. Deregulation in metabolism and DNA oxidative damage is shown to be responsible for increasing cancer risk, but the triggering pathway is unclear. The tendency to develop diseases in both genders is heterozygous, and a larger dataset is required to draw a conclusion.

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Respiratory health risk assessment of children living close to industrial areas in Indonesia

Cited by 7 publications

References 1 publication

Tobacco smoking and risk of all-cause mortality in Indonesia

Tobacco smoking and risk of all-cause mortality in Indonesia

Long-term exposure to PM2.5 and Children’s lung function: a dose-based association analysis

Industrial pollutions on the health effects of infants, children, and adolescents: A systematic review

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