VC on Monday were recorded in subjects with and without byssinosis with a significantly larger mean reduction in byssinotics (FEV1.0, P < 0-01; Vmax 50% VC, P < 0 05). Vmax 50 % VC proved to be a more sensitive test for detecting acute effects of vegetable dust than FEV1.o. The acute respiratory response of the subjects exposed to similar concentrations of flax and mixtures of two different proportions of flax and hemp dust was found to be equal.