Resource Use and Cost of Alzheimer’s Disease in France: 18-Month Results from the GERAS Observational Study

Rapp, Thomas; Andrieu, Sandrine; Chartier, F.; Deberdt, Walter; Reed, Catherine; Belger, Mark; Vellas, Bruno

doi:10.1016/j.jval.2017.09.019

Cited by 27 publications

(32 citation statements)

References 27 publications

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“…These figures are in line with those obtained for other rare disorders [21]. The number of hours of informal care needed by SMA patients is very similar to the time needed by patients with other low-prevalence diseases, such as Duchenne muscular dystrophy [32], mucopolysaccharidosis [33] or juvenile idiopathic arthritis [34], and by patients with other high-prevalence diseases that cause a severe loss of personal autonomy, such as stroke [35] or Alzheimer's disease [36,37].…”

Section: Discussionsupporting

confidence: 82%

The Burden of Spinal Muscular Atrophy on Informal Caregivers

Aranda-Reneo

Peña-Longobardo

Oliva‐Moreno

et al. 2020

IJERPH

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Spinal muscular atrophy (SMA) is one of the most common severe hereditary diseases of infancy and early childhood. The progression of this illness causes a high degree of disability; hence, a significant burden is experienced by individuals with this disease and their families. We analyzed the time taken to care for patients suffering from SMA in European countries and the burden on their informal caregivers. We designed a cross-sectional study recording data from France, Germany, Spain and the United Kingdom. The primary caregivers completed a self-administered questionnaire that included questions about the time of care, The Zarit Burden Interview, type of SMA and socio-demographic characteristics. Multivariate analyses were used to study the associations between the type of SMA, time of care and burden supported by informal caregivers. The caregivers provided 10.0 h (SD = 6.7) per day of care (the principal caregivers provided 6.9 h, SD = 4.6). The informal caregivers of patients with type I SMA had a 36.3 point higher likelihood (p < 0.05) of providing more than 10 h of care per day in comparison with caregivers of patients with type III SMA. The severity of the disease was associated with more time of care and a higher burden on the caregivers.

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Section: Discussionsupporting

confidence: 82%

The Burden of Spinal Muscular Atrophy on Informal Caregivers

Aranda-Reneo

Peña-Longobardo

Oliva‐Moreno

et al. 2020

IJERPH

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“…The families of those individuals who are not eligible to receive benefits assume the total extended shadow cost sharing. In addition, our results support the overburden of the informal caregiver when the severity of the disease increases [51,80], such as dementia [81], Alzheimer's disease [82] or cancer [83,84].…”

Section: Discussionsupporting

confidence: 68%

Shadow and extended shadow cost sharing associated to informal long-term care: the case of Spain

et al. 2020

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Background: A large part of the long-term care is provided by non-professional caregivers, generally without any monetary payment but a value economic of time invested. The economic relevance of informal caregivers has been recognized in Spain; however, public provision may still be scarce. The objective of this paper is to estimate the economic burden associated with informal long-term care that should assume the families through a new concept of cost sharing that consider opportunity costs of time provided by informal caregivers. Methods: The study sample includes all dependent adults in Spain. Socioeconomic information and the number of hours of informal care was collected through the Spanish Disability and Dependency Survey. The terms of shadow and extended shadow cost sharing were defined as the difference between the maximum potential amount of money that families could receive for the provision of informal care and the amount that actually they received and the value of informal care time with respect to the amount received, respectively. Results: 53.87% of dependent persons received an economic benefit associated to informal care. The average weekly hours of care were 71.59 (92.62 without time restrictions). Shadow cost sharing amounted to, on average, two thirds, whereas the State financed the remaining third. In terms of extended shadow cost sharing, the State financed between 3% and 10% of informal care provided by caregivers. Conclusions: This study reveals the deficient support received for the provision of informal care in Spain. More than 90% of informal care time is not covered by the economic benefits that families receive from the State.

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“…Of publications reporting unit costs or cost sources, fewer were identified for France ( n = 9) [ 30 – 37 ] than for Germany ( n = 15) [ 23 , 38 – 50 ] or Italy ( n = 15) [ 51 – 64 ], with one study reporting data for all three countries [ 65 ]. A range of cost sources and unit costs could be obtained from these studies for the resource use items of interest (Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Costs and where to find them: identifying unit costs for health economic evaluations of diabetes in France, Germany and Italy

Pöhlmann¹,

Norrbacka²,

Boye

et al. 2020

Eur J Health Econ

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Background Health economic evaluations require cost data as key inputs. Many countries do not have standardized reference costs so costs used often vary between studies, thereby reducing transparency and transferability. The present review provided a comprehensive overview of cost sources and suggested unit costs for France, Germany and Italy, to support health economic evaluations in these countries, particularly in the field of diabetes. Methods A literature review was conducted across multiple databases to identify published unit costs and cost data sources for resource items commonly used in health economic evaluations of antidiabetic therapies. The quality of unit cost reporting was assessed with regard to comprehensiveness of cost reporting and referencing as well as accessibility of cost sources from published cost-effectiveness analyses (CEA) of antidiabetic medications. Results An overview of cost sources, including tariff and fee schedules as well as published estimates, was developed for France, Germany and Italy, covering primary and specialist outpatient care, emergency care, hospital treatment, pharmacy costs and lost productivity. Based on these sources, unit cost datasets were suggested for each country. The assessment of unit cost reporting showed that only 60% and 40% of CEAs reported unit costs and referenced them for all pharmacy items, respectively. Less than 20% of CEAs obtained all pharmacy costs from publicly available sources. Conclusions This review provides a comprehensive account of available costs and cost sources in France, Germany and Italy to support health economists and increase transparency in health economic evaluations in diabetes.

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Resource Use and Cost of Alzheimer’s Disease in France: 18-Month Results from the GERAS Observational Study

Abstract: Increasing severity of AD dementia in France is associated with increased use of resources as well as increased total societal and patient costs; informal care was the greatest cost contributor. Clinically meaningful cognitive decline is associated with significantly increased costs.

Cited by 27 publications

References 27 publications

The Burden of Spinal Muscular Atrophy on Informal Caregivers

The Burden of Spinal Muscular Atrophy on Informal Caregivers

Shadow and extended shadow cost sharing associated to informal long-term care: the case of Spain

Costs and where to find them: identifying unit costs for health economic evaluations of diabetes in France, Germany and Italy

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