Resonance light scattering determination of trace bisphenol A with signal amplification by aptamer–nanogold catalysis

Yao, Dongmei; Liang, Aihui; Wang, Yin; Jiang, Zhiliang

doi:10.1002/bio.2578

Cited by 12 publications

(2 citation statements)

References 34 publications

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“…Aptamer is a small oligonucleotide sequence or short polypeptide that can speci cally recognize the target obtained by systematic evolution of ligands by exponential enrichment (SELEX) technology [23][24][25]. As a new type of biosensor identi cation element, it can be applied to the detection of food [26], drugs [27], viruses and other aspects [28], and also have a broad application in the eld of biological imaging [29]. This work combines carbon dots with aptamers, that is, combines the excellent uorescence performance and low toxicity of carbon dots with the advantages of aptamers for speci c detection of the detection substance, and constructs a simple and convenient uorescence aptamer sensor.…”

Section: Introductionmentioning

confidence: 99%

A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone

et al. 2022

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In this paper, a uorescent aptamer sensor was constructed based on the carbon dots and graphene oxide. This sensor combines the excellent uorescence performance of carbon dots with the high speci city of aptamers to detect progesterone with high sensitivity and selectivity. In the absence of progesterone, the carbon dots-aptamer system and graphene oxide form a uorescence resonance energy transfer process(FRET), which quenches the uorescence of the carbon dots. When progesterone is added, the aptamer speci cally binds to progesterone, resulting the uorescence of the carbon dots is recovered. At optimal conditions, the uorescence intensity recovered by the carbon dots has a linear relationship with the concentration of progesterone in the range of 0.1-120 nM, and the detection limit is 3.3×10 -11 M. Besides, the sensor has satisfactory detection results of progesterone in milk, indicating that this method has a enormous potential for application in food safety.

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Section: Introductionmentioning

confidence: 99%

A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone

et al. 2022

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“…BPA threatens health through food, when it is present in a container during food heating [38]. The main methods of detecting BPA include chromatography [39,40], absorption spectroscopy [41,42], fluorimetry [43,44], electrochemistry methods [45], resonance Rayleigh scattering (RRS) [46,47], and surface-enhance Raman spectroscopy [48,49]. However, these methods exhibit low selectivity and low sensitivity or require precious and expensive instrumentation.…”

Section: Introductionmentioning

confidence: 99%

Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection

et al. 2022

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Carbon dots (CDs) can be prepared from various organic (abundant) compounds that are rich in surfaces with –OH, –COOH, and –NH2 groups. Therefore, CDs exhibit good biocompatibility and electron transfer ability, allowing flexible surface modification and accelerated electron transfer during catalysis. Herein, CDs were prepared using a hydrothermal method with fructose, saccharose, and citric acid as C sources and urea as an N dopant. The as-prepared CDs were used to catalyze AgNO3–trisodium citrate (TSC) to produce Ag nanoparticles (AgNPs). The surface-enhanced Raman scattering (SERS) intensity increased with the increasing CDs concentration with Victoria blue B (VBB) as a signal molecule. The CDs exhibited a strong catalytic activity, with the highest activity shown by fructose-based CDs. After N doping, catalytic performance improved; with the passivation of a wrapped aptamer, the electron transfer was effectively disrupted (retarded). This resulted in the inhibition of the reaction and a decrease in the SERS intensity. When bisphenol A (BPA) was added, it specifically bound to the aptamer and CDs were released, recovering catalytical activity. The SERS intensity increased with BPA over the concentration range of 0.33–66.67 nmol/L. Thus, the aptamer-adjusted nanocatalytic SERS method can be applied for BPA detection.

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Chemiluminescence‐based aptasensors for various target analytes

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2018

Luminescence

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Aptamers (DNA or RNA) have complex three‐dimensional shapes that can bind to specific targets. Relative to antibodies, aptamers benefit from their low cost of production, easy chemical modification, high chemical stability, reproducibility, and low levels of immunogenicity and toxicity. However, the true value of aptamers lies in their simplicity by which these molecules can be engineered into sensors as bio‐recognition elements in diagnostics, drug discovery and therapy, environmental monitoring and food quality testing, etc. Many different types of techniques, such as optical, electrochemical, radiochemical and piezoelectronic methods, have been applied for the design of aptamer‐based methods, in which chemiluminescence (CL) detection techniques have become very popular in recent years. This review focuses on the recent advances in the development of aptamer‐based CL sensors for different target detection. We highlight specific examples that showcase the use of aptamers in practical applications, and provide the challenges and opportunities in this promising field.

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Resonance light scattering determination of trace bisphenol A with signal amplification by aptamer–nanogold catalysis

Cited by 12 publications

References 34 publications

A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone

A Significant Fluorescent Aptamer Sensor Based on Carbon Dots and Graphene Oxide for Highly Selective Detection of Progesterone

Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection

Chemiluminescence‐based aptasensors for various target analytes

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