Resonance Effect of Microwaves on the Genome Conformational State of E. coli Cells

Abstract

The effect of low intensity microwaves on the conformational state of the genome of X-irradiated E. coli cells was studied by the method of viscosity anomalous time dependencies. It has been established that within the ranges of 51.62-51.84 GHz and 41.25-41.50 GHz the frequency dependence of the observed effect has a resonance nature with a resonance halfwidth of the order of 100 MHz. The power dependence of the microwave effect within the range of 0.1-200 (μW/cm2 has shown that a power density of 1 μW/cm2 is sufficient to suppress radiation-induced repair of the genome conformational state. The effect of microwave suppression of repair is well reproduced and does not depend on the sequence of cell exposure to X-rays and microwave radiation in the millimeter band. The results obtained indicate the role of the cell genome in the resonant interaction of cells with low intensity millimeter waves.

Microwaves from UMTS/GSM mobile phones induce long‐lasting inhibition of 53BP1/γ‐H2AX DNA repair foci in human lymphocytes

“…Our previous data have shown that MWs at specific frequencies inhibit repair of radiation-induced DNA damage in E. coli cells [Belyaev et al, 1992b[Belyaev et al, , 1993. Thus, our working hypothesis was that a decrease in 53BP1/g-H2AX foci could be a manifestation of the inhibitory effects of MW on repair of spontaneous DSBs.…”

“…Among other dependencies, the dependence of non-thermal effects of MWs on frequency has been reported [Pakhomov et al, 1998;Belyaev et al, 2000]. Frequency-dependent interactions of MWs with such targets as cellular membranes, chromosomal DNA, radicals, proteins and ions in protein cavities may be involved in effects of MWs [Ismailov, 1987;Belyaev et al, 1992b;Chiabrera et al, 2000;Binhi, 2002;de Pomerai et al, 2003;Ritz et al, 2004]. However, there is substantial lack of knowledge in biophysical modeling of MW-induced non-thermal biological effects.…”

Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation

“…There is substantial lack of knowledge in biophysical modeling of MW-induced nonthermal biological effects [Adey, 1999;Binhi, 2002]. Such targets as DNA, radicals, proteins and ions in protein cavities may be involved in effects of MWs [Belyaev et al, 1992;Chiabrera et al, 2000;Binhi, 2002;de Pomerai et al, 2003;Ritz et al, 2004].…”

Resonance effect of millimeter waves in the power range from 10-19 to 3 × 10-3 W/cm2 onEscherichia coli cells at different concentrations

“…1) has already been described [Belyaev et al, 1992a. Voltage standing wave ratio (VSWR) in the waveguide system was measured by means of a measuring instrument at 1 mW incident power.…”

“…The MMW effects were examined by using the method of anomalous viscosity time dependencies (AVTD). A correlation of the AVTD measurements with the GCS changes was examined and discussed previously [Belyaev et al, 1992a. In this study, we provided new evidence for such correlation by using ethidium bromide, which is known as a specific intercalating drug for DNA [Cook and Brazell, 19761.…”