Resolution of (±)-menthol by immobilized lipase on superparamagnetic nanoparticles

Bai, Shu; Guo, Zheng; Liu, Wei; Sun, Yan

doi:10.1016/j.foodchem.2005.01.047

Cited by 81 publications

(43 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ideally, these NPs could bear a pharmaceutical drug that could be driven to the target organ and be released there. Resolution of ( ± ) menthol [186] 4) Hyperthermia Magnetic particles embedded around a tumor site and placed within an oscillating magnetic fi eld will heat up. Cancer cells are destroyed at lower temperatures than the normal cells.…”

Section: Applicationsmentioning

confidence: 99%

Enzyme Immobilization on Layered and Nanostructured Materials

Pavlidis

Tzialla

Enotiadis

et al. 2010

Biocatalysis in Polymer Chemistry

View full text Add to dashboard Cite

Section: Applicationsmentioning

confidence: 99%

Enzyme Immobilization on Layered and Nanostructured Materials

Pavlidis

Tzialla

Enotiadis

et al. 2010

Biocatalysis in Polymer Chemistry

View full text Add to dashboard Cite

“…An optimum enzyme loading is preferred to increase its application efficiency [18], especially for enzyme immobilization. The effect of enzyme loading was studied for lipase immobilization on a sponge layer of an EMR.…”

Section: Effect Of Enzyme Loadingmentioning

confidence: 99%

Enantioseparation of (R,S)‐ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor

Ong

Kamaruddin²,

Bhatia

et al. 2008

J of Separation Science

View full text Add to dashboard Cite

An enzymatic membrane reactor (EMR) for enantioseparation of (R,S)-ketoprofen via Candida antarctica lipase B (CALB) as biocatalyst was investigated. A comparative study of free and immobilized CALB was further conducted. The catalytic behaviour of CALB in an EMR was affected by the process parameters of enzyme load, substrate concentration, substrate molar ratio, lipase solution pH, reaction temperature, and substrate flow rate. Immobilization of CALB in the EMR was able to reduce the amount of enzyme required for the enantioseparation of (R,S)-ketoprofen. Immobilized CALB in the EMR assured higher reaction capacity, better thermal stability, and reusability. It was also found to be more cost effective and practical than free CALB in a batch reactor.

show abstract

“…Deste modo, a modificação de superfícies destas nanopartículas de magnetita torna-se necessária para que as mesmas desempenhem as suas aplicações. (Montero et al, 1993;Arroyo, Sanchez-Montero, Sinisterra, 1999;Huang, Liao, Chen, 2003;Gardimalla et al, 2005;Bai et al, 2006;Mateo et al, 2007;Yong et al, 2008;Fernandez-Lorente et al, 2008;Lee et al, 2009). …”

Section: Introductionunclassified

PRODUÇÃO DE ISONIAZIDA POR BIOCATÁLISE USANDO LIPASE DO TIPO B DE Candida antarctica IMOBILIZADA EM NANOPARTICULAS MAGNÉTICAS

Gonçalves¹,

Costa²,

Lima³

et al. 2015

Anais Do XX Congresso Brasileiro De Engenharia Química

View full text Add to dashboard Cite

RESUMO -A Isoniazida (INH) ou hidrazida do ácido 4-piridinocarboxílico é um destacado fármaco usado no tratamento da tuberculose. INH é preparado, convencionalmente, partindo da hidrólise da 4-cianopiridina, processo que ocorre com grande dispêndio energético e conduzida com uso de substâncias nocivas como é o caso da 4-cianopiridina, que além de nociva é preparada a partir da 4-picolina, que tem um elevado custo. Recentemente, estudos mostraram que a INH pode ser produzida em processos catalisados por lipases, conduzidos em condições amenas. Neste trabalho, apresentamos a aplicação de lipase do tipo B de Candida antarctica (CALB) imobilizada em sistemas biocatalíticos magnéticos nanoparticulados (CALB-NPM) para a produção de INH. Conversões próximas à 18,0% e atividade de hidrazinólise igual à 0,16±0,03 Mol/mg.mL.h foram atingidas neste trabalho e apresentam-se como resultados promissores apontando para a viabilidade do uso de CALB-NPM como biocatalisador na produção de INH.

show abstract

Resolution of (±)-menthol by immobilized lipase on superparamagnetic nanoparticles

Cited by 81 publications

References 26 publications

Enzyme Immobilization on Layered and Nanostructured Materials

Enzyme Immobilization on Layered and Nanostructured Materials

Enantioseparation of (R,S)‐ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor

PRODUÇÃO DE ISONIAZIDA POR BIOCATÁLISE USANDO LIPASE DO TIPO B DE Candida antarctica IMOBILIZADA EM NANOPARTICULAS MAGNÉTICAS

Contact Info

Product

Resources

About