Resolution of chronic urticaria in patients with thyroid autoimmunity

Rumbyrt, Jeffrey; Katz, Joel L.; Schocket, Alan L.

doi:10.1016/s0091-6749(95)70226-1

Cited by 125 publications

(89 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Em estudos onde foi encontrada maior prevalência de DAT em pacientes com UC, observou-se melhora das lesões de pele em alguns pacientes após tratamento com levotiroxina (8,22,23). Os autores sugerem que existe uma relação de causa e efeito, ou seja, DAT levaria ao desencadeamento da UCI.…”

Section: Discussionunclassified

Avaliação da associação entre doença auto-imune de tireóide e urticária crônica idiopática

Feibelmann

Gonçalves

Daud

et al. 2007

Arq Bras Endocrinol Metab

View full text Add to dashboard Cite

Vários estudos encontraram maior prevalência de Doença Auto-imune de Tireóide (DAT) em pacientes com Urticária Crônica (UC). Essa relação pode ocorrer devido à possível etiologia auto-imune em até um terço dos casos de Urticária Crônica Idiopática (UCI). No entanto, a freqüência de DAT variou de 1,14% a 28,6%. O princípio deste estudo foi determinar se ocorre associação entre DAT e UCI em uma população atendida em um mesmo centro de saúde. Comparamos a freqüência de anticorpos anti-tireoidianos e disfunção tireoidiana entre 49 pacientes com UCI (grupo 1) e 112 controles (grupo 2). Com a finalidade de fortalecer o resultado encontrado, estudamos a prevalência de UCI em 60 pacientes com DAT (grupo 3) comparados com 29 com doença não auto-imune de tireóide (DNAT) (grupo 4). Não encontramos diferença estatística quanto à presença de anticorpos anti-tireoidianos ou disfunção tireoidiana entre os grupos 1 e 2 (12,24% x 9,82% e 12,24% x 7,14%, respectivamente). O mesmo ocorreu quanto à presença de UCI entre os grupos 3 e 4 (3,33% x 3,44%). Em nosso estudo não foi possível demonstrar uma relação entre DAT e UCI, o que significa que diferentes populações podem apresentar maior ou menor grau de associação entre essas doenças.

show abstract

Section: Discussionunclassified

Avaliação da associação entre doença auto-imune de tireóide e urticária crônica idiopática

Feibelmann

Gonçalves

Daud

et al. 2007

Arq Bras Endocrinol Metab

View full text Add to dashboard Cite

show abstract

“…Warren R Heymann 17 has stated that there is a clustering of thyroid microsomal antibodies in patients with positive autologous serum test, although it is unlikely that thyroid hormone itself has any in vivo effect on the cutaneous vascular response to histamine and on mast cell releasability. 18 Acrochordons were noted in 11.11% of patients in our study. Rezzonico et al concluded that individuals with skin tags have high prevalence of thyroid nodules and thyroid with increased volume.…”

Section: Associationsmentioning

confidence: 45%

Study of Cutaneous Manifestations in Thyroid Disorders

Sindhu¹,

Reddy²,

Netha³

et al. 2016

jemds

View full text Add to dashboard Cite

BACKGROUNDThyroid disorders are known to involve all organ systems of the body, the skin being no exception.The present study is aimed to study various cutaneous manifestations and see cutaneous manifestations in thyroid disorders and to know various dermatologic associations of thyroid disorders. MATERIALS AND METHODSThis is a prospective, observational study conducted over a period of 18 months in Department of DVL in a Tertiary Care Centre. All patients with thyroid abnormality and cutaneous manifestations are included in the study. Detailed clinical examination is done and the findings are recorded. RESULTSThyroid disorders are more common in females. The most common age group affected by hypothyroidism was 31 -40 years, hyperthyroidism is 21 -30 yrs. Weight gain and dry skin were the commonest symptoms among hypothyroid patients and heat intolerance and increased sweating were commonest among hyperthyroid patients. Xerosis and dry, rough, coarse skin among hypothyroid patients; and warm, soft, velvety skin among hyperthyroid were commonest findings. Urticaria was the most common autoimmune association noted among hypothyroid patients. CONCLUSIONWith our study, it could be concluded that a better understanding complex interaction between skin and thyroid may help us not only to diagnose underlying thyroid abnormality, but also to monitor response of cutaneous features with treatment. Both abnormally low and excessively high serum levels of thyroid hormones can alter the appearance and function of human skin and its appendages. The prevalence of cutaneous changes with thyroid disorders varied from 39% to 100% in different studies. With such a high prevalence of cutaneous manifestations in thyroid disorders, the present study is aimed to study various cutaneous manifestations and see if cutaneous manifestations aid in early diagnosis and hence treatment of patients with abnormal thyroid function. Most common cause of abnormalities in thyroid function being autoimmune in aetiology show an association with other autoimmune disorders. Financial or Other, Competing Interest: None. Submission 22-11-2016, Peer Review 15-12-2016, Acceptance 22-12-2016, Published 29-12-2016. Corresponding Author: Dr. Kotha Raghupathi Reddy, # 2-1-15/4, Near Old Ramalayam, Nallakunta, Hyderabad-500044, Telangana State. E-mail: krrya7@gmail.com DOI: 10.14260/jemds/2016/1731 The present study also tries to outline the most common dermatologically relevant autoimmune associations of thyroid disease.Aims and Objectives 1. To study various cutaneous manifestations of hypothyroidism and hyperthyroidism. 2. To study various dermatologic disorders associated with thyroid disorders. MATERIALS AND METHODSThis is a prospective, observational study conducted over a period of 18 months in Department of DVL in a tertiary hospital. All patients with thyroid abnormality and cutaneous manifestations, either presenting to Dermatology OPD or referred from other Departments are included in the study after taking an informed consent. Dem...

show abstract

“…25 The pathophysiology of the association is not well understood, but it seems that anti-thyroid antibodies are not directly responsible for the lesions seen in patients and only serve as an indicator of autoimmunity. 27 Interest in this topic has increased, because it has been reported that urticaria improves with normalization of thyroid function. [22][23][24]27 In agreement with other reports, 9,17,25 HT was the most frequently detected ATD (77.3%) in our patients, and was observed in 14.8% of the CIU cases.…”

Section: Discussionmentioning

confidence: 99%

“…27 Interest in this topic has increased, because it has been reported that urticaria improves with normalization of thyroid function. [22][23][24]27 In agreement with other reports, 9,17,25 HT was the most frequently detected ATD (77.3%) in our patients, and was observed in 14.8% of the CIU cases. Camargo et al found a similar rate of chronic thyroiditis among 829 individuals from a general population in the city of São Paulo (17.6%).…”

Section: Discussionmentioning

confidence: 99%

Autoimmune thyroid disease as a risk factor for angioedema in patients with chronic idiopathic urticaria: a case-control study

Missaka¹,

Penatti²,

Silvares

et al. 2012

Sao Paulo Med. J.

View full text Add to dashboard Cite

CONTEXT AND OBJECTIVE: An association between chronic idiopathic urticaria (CIU) and autoimmune thyroid disease (ATD) has been reported. However, there have not been any reports on whether ATD raises the risk of angioedema, which is a more severe clinical presentation of CIU. Thus, the aim of the present study was to evaluate whether the risk of angioedema is increased in patients with CIU and ATD. DESIGN AND SETTING: Case-control study including 115 patients with CIU at a tertiary public institution. METHODS:The patients were evaluated with regard to occurrence of angioedema and presence of ATD, hypothyroidism or hyperthyroidism. RESULTS: Angioedema was detected in 70 patients (60.9%).

show abstract

Resolution of chronic urticaria in patients with thyroid autoimmunity

Cited by 125 publications

References 8 publications

Avaliação da associação entre doença auto-imune de tireóide e urticária crônica idiopática

Avaliação da associação entre doença auto-imune de tireóide e urticária crônica idiopática

Study of Cutaneous Manifestations in Thyroid Disorders

Autoimmune thyroid disease as a risk factor for angioedema in patients with chronic idiopathic urticaria: a case-control study

Contact Info

Product

Resources

About