Resistensi Antibakteri pada Pasien Infeksi Saluran Kemih (ISK) dengan Kateterisasi Urin di Bagian Penyakit Dalam RSUD Arifin Achmad Pekanbaru

Abstract

Uninary tract infection (UTI) is a common health problem among the people in the world, including Indonesia.Approximately 80% of UTI in hospital are ascociated with urethral catheter used in hospitalized patients. The increaseof catheter- related UTI is olso followed by increase of antibiotic used. The diffrence in distribution of UTI causingbacteria and antibiotics resistance associated with cathetetization can change according to time and place. This stdyaims to find the pattern of antibiotic resistance in the urine of catheter related UTI patient. The research was done inDepartement of Internal Medicine RSUD arifin Achmad Pekanbaru. 31 samples were collected from hospitalizedpatient who used catheter at last 3 days and taken with indwelling catheter urine. Culture, colony count, colonyidentification and resistance test was performed by Kirby Bauer method. The result was interpretated based onClinical and Laboratory Standard Institude (CLSI). UTI found in 19 samples (61.29%), 9 samples founs no bacteria(29.03%) and Candida albicans on 3 samples (9.68%). UTI caused mostly by Gram-negative bacteria (57.89%),Gram- positive bacteria found in 42.11% of samples. The highest resistance (100%) was found on cefotaxim, cefriaxon,cefalexin and tertracyclin. The lowest resistance (73.68%) found on merofenem and co-trimoxazole.

Pola Resistensi Antibiotik Bakteri Penyebab Infeksi Saluran Kemih di Puskesmas Ibrahim Adjie Kota Bandung

“…Di Rumah Sakit PKU Muhammadiyah Yogyakarta E. coli penyebab ISK masih sensitif terhadap imipenem dan sudah mengalami resistansi terhadap siprofloksasin, gentamisin, trimetroprim-sulfametoksazol, amoksisilin dan sefiksim [30]. Sedangkan E. coli yang diisolasi dari pasien ISK di RSUD Arifin Achamd Pekanbaru sudah reisiten terhadap ampisilin, sefalotin, sefotaksim, seftriakson, sefaleksin dan tetrasiklin [11].…”

“…Namun imipenem masih aktif terhadap bakteri tersebut [8]. Di Indonesia, E. coli juga merupakan bakteri penyebab ISK terbanyak [9][10][11]. Sedangkan pada suatu rumah sakit di Banda Aceh bakteri penyebab ISK yang terbanyak adalah Pseudomonas aeruginosa [12].…”

Antibacterial and Characterization of Secondary Metabolite Compound from Ethyl Acetate and Ethanol Fraction of Leaves Moringa oliefera L

“…This mechanism is a self-defense mechanism for microorganisms to be able to survive (Brooks et al, 2013). The highest resistance found in antibiotics penicillin and cephalosporin first generation (Yacob et al, 2011).…”