Resistance exercise alone improves muscle strength in growth hormone deficient males in the transition phase

Amer, Nadia Mohamad; Modesto, Marilza J.; Santos, Claudia Duarte; Erichsen, Oscar; Mascarenhas, Luís Paulo Gomes; Nesi-França, Suzana; Marques-Pereira, Rosana; Lacerda, Luiz de

doi:10.1515/jpem-2017-0369

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…Rh-GH should not be used during the transition with the only aim of muscle growth, even though several studies have shown clear lower muscle strength in confirmed GHD subjects compared to sufficient or healthy controls ( 43 ). A recent study assessed how 12 weeks of resistance exercise alone could improve muscle strength during the transition ( 44 ). Interesting is the interconnection between GH, leptin and ghrelin.…”

Section: The Role Of Gh During Transition: Effects On Bone Body Compmentioning

confidence: 99%

Clinical, Diagnostic, and Therapeutic Aspects of Growth Hormone Deficiency During the Transition Period: Review of the Literature

et al. 2021

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The role of growth hormone (GH) during childhood and adulthood is well established. Once final stature is reached, GH continues to act during the transition, the period between adolescence and adulthood in which most somatic and psychological development is obtained. The achievement of peak bone mass represents the most relevant aspect of GH action during the transition period; however, equally clear is its influence on body composition and metabolic profile and, probably, in the achievement of a complete gonadal and sexual maturation. Despite this, there are still some aspects that often make clinical practice difficult and uncertain, in particular in evaluating a possible persistence of GH deficiency once final stature has been reached. It is also essential to identify which subjects should undergo re-testing and, possibly, replacement therapy, and the definition of unambiguous criteria for therapeutic success. Moreover, even during the transition phase, the relationship between GH substitution therapy and cancer survival is of considerable interest. In view of the above, the aim of this paper is to clarify these relevant issues through a detailed analysis of the literature, with particular attention to the clinical, diagnostic and therapeutic aspects.

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Section: The Role Of Gh During Transition: Effects On Bone Body Compmentioning

confidence: 99%

Clinical, Diagnostic, and Therapeutic Aspects of Growth Hormone Deficiency During the Transition Period: Review of the Literature

et al. 2021

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Maturity-Associated Variations in Resistance Exercise-Induced Hormonal Responses in Young Male Athletes

Sekine

Hirose

2022

Pediatric Exercise Science

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Purpose: To examine differences in resistance exercise-induced hormonal responses among young athletes according to their maturity levels. Materials and Methods: A total of 12 collegiate and 32 junior high school male athletes were enrolled. The junior high school participants were divided into pre–peak height velocity (PHV) and post-PHV groups, according to their PHV ages. The salivary testosterone, cortisol, and human growth hormone levels were analyzed before (pre), immediately after (post), and at 15 minutes after performing body weight resistance exercise. Results: The testosterone levels were higher in the collegiate than in the junior high school group (P < .01) and increased after 15 minutes of exercise (P < .01). A significant decrease in the cortisol levels postexercise in the junior high school groups (P < .01) and an increase in the human growth hormone levels at 15 minutes after exercise in the post-PHV group were observed (P < .01). In the collegiate and post-PHV groups, the testosterone-to-cortisol ratio increased post and at 15 minutes after exercise (P < .01). The testosterone-to-cortisol ratio values were higher in the collegiate than in the post-PHV (at preexercise and at 15 min after [P < .01]) and pre-PHV groups (at all times [P < .01]). Conclusion: Exercise-induced acute hormonal responses to resistance exercise may depend on individuals’ maturity levels, even in those having the same age.

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Resistance exercise alone improves muscle strength in growth hormone deficient males in the transition phase

Cited by 2 publications

References 37 publications

Clinical, Diagnostic, and Therapeutic Aspects of Growth Hormone Deficiency During the Transition Period: Review of the Literature

Clinical, Diagnostic, and Therapeutic Aspects of Growth Hormone Deficiency During the Transition Period: Review of the Literature

Maturity-Associated Variations in Resistance Exercise-Induced Hormonal Responses in Young Male Athletes

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