This cross-sectional study explored the prevalence of stressful life experiences (SLEs) and their relationship with health conditions among older adults in Bhutan. A faceto-face interview was completed at homes and community settings. A total of 337 people aged 60 to 101 years were recruited from stupas, temples and local markets in four geographic regions. Measurements included checklists of Stressful Life Events (SLEs) and chronic health conditions, Kessler psychological distress scale (K10) and WHO-5 Wellbeing Index. Frequent back pain, memory decline, depression, mobility impairment, insomnia, and disease of the lungs were most common significantly different between the genders. Older adults in Bhutan had a complex variety of health conditions influenced by SLEs. Compared to participants with 1-5 SLEs, those with 8-14 SLEs had the higher odds of self-rating poor health by twofold (OR=2.07; 95%CI: 1.22-3.52). Comprehensive healthcare should address SLEs to mitigate their impact on health and improve overall quality of life and wellbeing of the person.