Residues and Safety Assessment of Cyantraniliprole and Indoxacarb in Wild Garlic (Allium vineale)

Abstract

In this study, the residual behavior and safety of cyantraniliprole and indoxacarb applied to wild garlic (Allium vineale) were investigated. Samples were harvested after treatments of 0, 3, 7, and 14 days, then were prepared and extracted following the QuEChERS method and analyzed by UPLC-MS/MS. The linearity (R2 ≥ 0.99) of the calibration curves was excellent for both compounds. The average recoveries of cyantraniliprole and indoxacarb at two spiking concentrations (0.01 and 0.1 mg/kg) ranged from 94.2% to 111.4%. The relative standard deviation value was below 10%. The initial concentrations of cyantraniliprole and indoxacarb in wild garlic were degraded to 75% and 93% after seven days. The average half-lives were 1.83 and 1.14 days for cyantraniliprole and indoxacarb, respectively. The preharvest intervals (PHIs) for the two pesticides in wild garlic are recommended as two treatments seven days before harvest. The safety assessment data indicated that the percent acceptable daily intakes of cyantraniliprole and indoxacarb were 0.3 × 10−4% and 06.7 × 10−2%, respectively, in wild garlic. The theoretical maximum daily intake value of cyantraniliprole was 9.80%, and that of indoxacarb was 60.54%. Both compounds’ residues in wild garlic pose low health risks to consumers. The findings of the current investigation provide essential data for the safe use of cyantraniliprole and indoxacarb in wild garlic.

Efectos subletales asociados a la resistencia a indoxacarb en la palomilla dorso de diamante

“…P. xylostella fue la primera especie en desarrollar resistencia al indoxacarb en el año 2001 (Zhao 2002) y en la actualidad, la resistencia a este químico en poblaciones de campo de P. xylostella se ha reportado a un nivel de medio a alto (Wang et al 2016). Indoxacarb es un insecticida del grupo de las oxadiazinas, se usa ampliamente para el control de larvas de lepidópteros (Wing et al 2010), tras su ingestión bloquea irreversiblemente los canales de sodio sensibles al voltaje en el sistema nervioso central de los insectos (Sardar et al, 2023), lo que provoca que se dejen de alimentar, causándoles una parálisis y posteriormente la muerte, sin embargo, este tóxico se considera de acción lenta y residual (Wang et al 2023a). Puede llegar a afectar el comportamiento y la fisiología de los insectos de manera crónica (Wang et al 2011), afectando la morfología, peso de las pupas, longevidad, alimentación, fecundidad (Zhang et al 2022) y diversos procesos fisiológicos y bioquímicos de los insectos, así como favorecer el desarrollo de la resistencia a los insecticidas (Quan et al 2016).…”