Residual Hepatic Damage in Catarrhal Jaundice as Determined by the Bilirubin Excretion Test

Electrophoretic Studies of the Serum Proteins in Virus Hepatitis

“…In the last few years there has been considerable interest (6)(7)(8)(9)(10)(11)(12)(13) in cases of hepatitis progressing to chronic liver disease, or developing post-necrotic cirrhosis. Except for the study by Martin (4), however, little information has been presented on the serum proteins after the acute stage of the disease.…”

The Biliary Excretion of Bromsulfalein as a Test of Liver Function in a Group of Patients Following Hepatitis or Serum Jaundice

“…The method of testing liver function by the biliary excretion of bromsulfalein has been described in detail previously and when further reference is made to it in this paper it will be called the biliary bromsulfalein test (22,23,27 (2) delayed appearance of the dye in the bile; (3) delayed attainment of the maximum concentration; (4) prolonged high curve (plateau-type) of excretion; (5) subnormal concentration (flat type of curve); (6) abnormally low total excretion in one-or two-hour periods after injection (28).…”

“…(Received for publication February 21, 1948) Prolonged or permanent impairment of liver function is now known to occur in a variable proportion of patients following an attack of infectious hepatitis or serum jaundice (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11). However, the incidence of this chronic hepatic disease is not well established because of the difficulty in correlating symptomatology with the available liver function tests or with liver biopsy (12)(13)(14)(15).…”

Infective Hepatic Jaundice

“…Some liver efficiency tests carried out by American observers (Soffer and Paulson, 1934) suggest that frequently the organ does not recover fully. The observations, however, are few and the tests themselves not of proven value.…”