Research Progress on Synthesis and Application of Cyclodextrin Polymers

Abstract

Cyclodextrins (CDs) are a series of cyclic oligosaccharides formed by amylose under the action of CD glucosyltransferase that is produced by Bacillus. After being modified by polymerization, substitution and grafting, high molecular weight cyclodextrin polymers (pCDs) containing multiple CD units can be obtained. pCDs retain the internal hydrophobic-external hydrophilic cavity structure characteristic of CDs, while also possessing the stability of polymer. They are a class of functional polymer materials with strong development potential and have been applied in many fields. This review introduces the research progress of pCDs, including the synthesis of pCDs and their applications in analytical separation science, materials science, and biomedicine.

Weakly acidic carboxy group-grafted β-cyclodextrin-threaded acid-degradable polyrotaxanes for modulating protein interaction and cellular internalization

“…Although it is difficult for carboxylated -CD PRXs to achieve selective targeting in macrophages, the high intracellular uptake of carboxylated -CD PRXs in MSR-A-negative cells is beneficial for their therapeutic application. The basic knowledge obtained in this study is expected to serve as an important guide for considering the molecular design of not only PRX, but also CD-based polymers in therapeutic applications [56]. 432 μg/mL) for 24 h. The data are expressed as the mean ± standard deviation (SD) (n = 3; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).…”

Cyclodextrin usage in textile Industry

“…Cyclodextrins(CDs) are cyclic oligosaccharides formed from potatoes, maize, rice, and so on via the enzyme starch degradation [1]. It is bio-consistent, biodegradable, environmentally sustainable, and clean.…”

Fabrication and Characterisation of Organic EL Devices in the Presence of Cyclodextrin as an Interlayer

“…The CDP has been evaluated as an iodine, polyphenols, and flavonoid adsorbent, adsorbent, water purifier and surfactant remover. Xiao Han et al introduced the research progress into CDPs and their applications in many fields [ 24 ]. A previous study reported an improvement in the function of CD using a photoelectric conversion element, namely a ‘Dye-sensitised solar cell with CD layer’, which is a similar eco-device, which is an absorbent material, has a photochromic reaction field and a cavity size effect for the absorbed material, respectively [ 25 , 26 , 27 ].…”