Research Progress on Surface-Enhanced Raman Spectroscopy Technique for the Detection of microRNA

Yi, Rongnan; Wu, Yan

doi:10.6023/a21010017

Acta Chimica Sinica

2021

DOI: 10.6023/a21010017

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Research Progress on Surface-Enhanced Raman Spectroscopy Technique for the Detection of microRNA

Rongnan Yi¹,

Yan Wu²

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Cited by 4 publications

References 77 publications

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Annealing treatment of focused gallium ion beam processing of SERS gold substrate

Tao

Zhao

Wang

et al. 2021

Nanotechnology and Precision Engineering

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Raman spectroscopy is a type of inelastic scattering spectroscopy that is widely used in determining and analyzing molecular structure. It also has a number of practical applications in evaluating food safety, medicine, and forensics. The Raman spectral signal is weak, but the development of the surface-enhanced Raman scattering (SERS) technique has overcome this problem and led to further developments in Raman spectroscopy. This paper describes a fundamental study of the use of focused ion beam (FIB) direct writing for preparing gold substrates for SERS. Molecular dynamics and Monte Carlo simulation methods are used to investigate the damage induced by gallium ion implantation of a gold substrate. Based on characterization by x-ray photoelectron spectroscopy (XPS) and scanning electron microscopy, the mechanism by which ion implantation and annealing influence the damage induced by a gallium FIB is analyzed. After annealing at 350 °C, a mixture of metallic gallium, its oxide Ga2O3 conforming to the stoichiometric ratio, and its sub-stable oxide (Ga2Ox) in sub-stoichiometric ratio precipitated on the surface are detected by XPS. Annealing treatment can effectively reduce the effect of gallium ion implantation on a SERS substrate fabricated by FIB direct writing.

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Annealing treatment of focused gallium ion beam processing of SERS gold substrate

Tao

Zhao

Wang

et al. 2021

Nanotechnology and Precision Engineering

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Surface-Enhanced Raman Scattering: 50 Years of Development and Its Role in Nanobiotechnology

Solovyeva

2024

Nanotechnol Russia

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The review covers the main stages in the development and achievements of surface-enhanced Raman scattering (SERS), the fiftieth anniversary of which we celebrate in 2024. Modern theoretical views on the SERS effect, a retrospective of the substrates and materials used, and expansion of the range of studied compounds and objects are presented. Using the example of the most important and interesting applications of SERS spectroscopy, the achievements of the last decade are considered; its role in modern surface chemistry, nanotechnology, bioanalysis and bioimaging methods is shown.

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Wastewater-Based Epidemiology: Assessing Illicit Drug Usage and Impact through an Innovative Approach

Yi,

Zeng,

Chen

et al. 2023

Water

Self Cite

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The abuse of illicit drugs, which is usually associated with violent crimes and public health issues, has evolved into a significant problem that the whole of society must address collectively. With the benefits of high productivity, convenience, objectivity, and semi-real time, wastewater-based epidemiology (WBE) has been demonstrated to be a powerful tool and has been utilized on a global scale for monitoring illicit drug use. In this review, we briefly introduce the development and application of WBE. Then, the stability of biomarkers is summarized, and methods to improve stability are introduced. We highlight recent advances in analytical techniques, from three aspects of chromatography–mass spectrometry, optical methods, and electrochemical strategies. The research progress of illicit drug abuse assessment based on WBE is summarized. Finally, we summarize the research hotspots and challenges on illicit drug abuse assessment based on WBE.

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Research Progress on Surface-Enhanced Raman Spectroscopy Technique for the Detection of microRNA

Cited by 4 publications

References 77 publications

Annealing treatment of focused gallium ion beam processing of SERS gold substrate

Annealing treatment of focused gallium ion beam processing of SERS gold substrate

Surface-Enhanced Raman Scattering: 50 Years of Development and Its Role in Nanobiotechnology

Wastewater-Based Epidemiology: Assessing Illicit Drug Usage and Impact through an Innovative Approach

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