Research progress on generation, detection and inhibition of multiple hazards - acrylamide, 5-hydroxymethylfurfural, advanced glycation end products, methylimidazole - in baked goods

Zhang, Z. Conrad; Chen, Yang; Deng, Peng; He, Zhiyong; Qin, Fang; Chen, Qiuming; Wang, Zhaojun; Pan, Hong; Chen, Jie; Zeng, Maomao

doi:10.1016/j.foodchem.2023.137152

Cited by 8 publications

(2 citation statements)

References 107 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acrylamide (AA) is a by-product of the Maillard reaction of asparagine with reducing sugars, such as glucose, galactose and fructose, at temperatures above 120 °C and peaking at around 170 °C [ 30 , 31 , 32 , 33 ]. AA is a genotoxic and neurotoxic compound, classified as level 2A since 1994 (probable human carcinogen) by the International Agency for Research on Cancer [ 34 , 35 , 36 ].…”

Section: Introductionmentioning

confidence: 99%

“…AA is a genotoxic and neurotoxic compound, classified as level 2A since 1994 (probable human carcinogen) by the International Agency for Research on Cancer [ 34 , 35 , 36 ]. Coffee is one of the main contributors to the intake of this hazard, as the roasting and spray-drying stages play an essential role in forming AA [ 33 , 37 ]. To ensure consumer protection on food safety, the European Commission has set a benchmark level of 8.50 × 10 −4 mg per kg of AA in instant coffee [ 38 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Probabilistic Risk Assessment of Metals, Acrylamide and Ochratoxin A in Instant Coffee from Brazil, Colombia, Mexico and Peru

Guadalupe,

Grandez-Yoplac,

Arellanos

et al. 2024

Foods

View full text Add to dashboard Cite

This study analysed the probabilistic risk to consumers associated with the presence of iAs, Cd, Cr, Hg, Pb, acrylamide (AA) and ochratoxin A (OTA) in instant coffee from Brazil, Colombia, Mexico and Peru. The results found iAs to be the metal with the highest concentrations (3.50 × 10−2 to 6.00 × 10−2 mg/kg), closely followed by Pb (1.70 × 10−2 to 2.70 × 10−2 mg/kg) and Cr (5.00 × 10−3 to 1.00 × 10−2 mg/kg), although these differences were not significant between countries. Cd and Hg were not detected. Focusing on AA, the concentrations ranged from 1.77 × 10−1 mg/kg (Peru) to 4.77 × 10−1 mg/kg (Brazil), while OTA ranged from 1.32 × 10−3 (Peru) to 1.77 × 10−3 mg/kg (Brazil) with significant differences between countries in both cases. As regards risk, the hazard quotient and hazard index were less than 1, meaning that the consumption of instant coffee represents a low level of concern for non-genotoxic effects. The results of the combination of margin of exposure and probability of exceedance indicated that the non-genotoxic effects of Pb, AA and OTA pose no threat. However, the probability values of suffering cancer from iAs and AA (between 1 × 10−6 and 1 × 10−4) indicated a moderate risk and that management measures should be taken.

show abstract