Research Progress of Titanium-Based High Entropy Alloy: Methods, Properties, and Applications

Ma, Ning; Liu, Shifeng; Liu, Wei; Xie, Lechun; Wei, Daixiu; Wang, Liqiang; Li, Lanjie; Zhao, Bin; Wang, Yan

doi:10.3389/fbioe.2020.603522

Cited by 46 publications

(16 citation statements)

References 139 publications

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“…Compared with other metals, copper has better antibacterial effect and biocompatibility. Numerous in vitro tests have demonstrated the low ion release of Cu-doped Ti implants prepared by various methods and their excellent cytocompatibility without cytotoxicity to MG63 [ 15 , 37 ], MC3T3-E1 [ 56 , 71 ], L929 [ 33 , 88 ] and other cells.…”

Section: Discussionmentioning

confidence: 99%

“…The main methods of alloy preparation include ingot metallurgy, powder metallurgy, selective laser melting etc. [ 56 ] Among them, arc melting [ 57 , 58 , 59 ] and powder metallurgy are the common methods for preparing alloys. The arc melting method involves introducing a certain percentage of the metal material into a clamp and then, after repeated evacuations, filling the vacuum furnace with protective argon gas.…”

Section: Preparation Techniques and Related Properties Of Cu-doped Ti...mentioning

confidence: 99%

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Recent Advances in Copper-Doped Titanium Implants

Zhou

Zeng

et al. 2022

Materials

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Titanium (Ti) and its alloys have been extensively used as implant materials in clinical practice due to their high corrosion resistance, light weight and excellent biocompatibility. However, the insufficient intrinsic osteogenic capacity of Ti and its alloys impedes bone repair and regeneration, and implant-related infection or inflammation remains the leading cause of implant failure. Bacterial infections or inflammatory diseases constitute severe threats to human health. The physicochemical properties of the material are critical to the success of clinical procedures, and the doping of Cu into Ti implants has been confirmed to be capable of enhancing the bone repair/regeneration, angiogenesis and antibacterial capability. This review outlines the recent advances in the design and preparation of Cu-doped Ti and Ti alloy implants, with a special focus on various methods, including plasma immersion implantation, magnetron sputtering, galvanic deposition, microarc oxidation and sol-gel synthesis. More importantly, the antibacterial and mechanical properties as well as the corrosion resistance and biocompatibility of Cu-doped Ti implants from different methods are systematically reviewed, and their prospects and limitations are also discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Preparation Techniques and Related Properties Of Cu-doped Ti...mentioning

confidence: 99%

Recent Advances in Copper-Doped Titanium Implants

Zhou

Zeng

et al. 2022

Materials

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“…Compared with traditional metals and alloys, high-entropy alloys are gradually becoming a focus of attention due to their better comprehensive properties. These alloys are no longer based on a particular component, but are made of a variety of metal to provide better properties such as strength, corrosion resistance, and biocompatibility (Ma et al, 2020). (Li et al, 2019b).…”

Section: High Entropy Alloysmentioning

confidence: 99%

Metal Material, Properties and Design Methods of Porous Biomedical Scaffolds for Additive Manufacturing: A Review

Wang

Liu

et al. 2021

Front. Bioeng. Biotechnol.

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Design an implant similar to the human bone is one of the critical problems in bone tissue engineering. Metal porous scaffolds have good prospects in bone tissue replacement due to their matching elastic modulus, better strength, and biocompatibility. However, traditional processing methods are challenging to fabricate scaffolds with a porous structure, limiting the development of porous scaffolds. With the advancement of additive manufacturing (AM) and computer-aided technologies, the development of porous metal scaffolds also ushers in unprecedented opportunities. In recent years, many new metal materials and innovative design methods are used to fabricate porous scaffolds with excellent mechanical properties and biocompatibility. This article reviews the research progress of porous metal scaffolds, and introduces the AM technologies used in porous metal scaffolds. Then the applications of different metal materials in bone scaffolds are summarized, and the advantages and limitations of various scaffold design methods are discussed. Finally, we look forward to the development prospects of AM in porous metal scaffolds.

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“…The first category is based on the crystallographic structure of the phase, and it includes FCC-based, BCC-based, HCP-based, amorphous, and intermetallic HEAs. The second category, based on the type of phase, includes single-phase, dual-phase, eutectic, and multi-phase HEAs [83].…”

Section: Trends In Enhancing Coatings Performances On Cocr Alloys and Other Metallic Alloys (Including High-entropy Alloys)mentioning

confidence: 99%

Sustainable Coatings on Metallic Alloys as a Nowadays Challenge

2021

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Starting with a description of the meaning of sustainable coating nowadays, this review presents a selection of methods for sustainable coatings manufacture using raw materials, saving energy and costs. This selection creates an introduction for the coatings performances of intensively investigated coated alloys and their multifunctionality. There are many examples and EU recommendations to be discussed, and we especially chose to introduce sustainable coatings with both industrial and medical functions, such as bioinspired films and coatings on high-entropy alloys, biodegradable metallic alloys, etc. A special focus is on nanotechnology and nanomaterials in green procedures, enhancing coatings’ multifunctionality, introducing green corrosion inhibitors, smart additives, and coatings based on superhydrophobicity. The conclusions and future perspectives of sustainable and multifunctional coatings, as expressions of sustainable advanced materials, are based on important motivations of such studies.

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Research Progress of Titanium-Based High Entropy Alloy: Methods, Properties, and Applications

Cited by 46 publications

References 139 publications

Recent Advances in Copper-Doped Titanium Implants

Recent Advances in Copper-Doped Titanium Implants

Metal Material, Properties and Design Methods of Porous Biomedical Scaffolds for Additive Manufacturing: A Review

Sustainable Coatings on Metallic Alloys as a Nowadays Challenge

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