“…The etiology of ITP remains unclear, but both genetic and environmental factors are thought to play role in the development of the disease. Several genes involved in immune system regulation like cytokine genes [3,4,5,6], Fc gamma receptor genes [4,7], CTLA-4 gene [8,9], and HLA genes [10], as well as some infective agents like hepatitis C virus, HIV (Human Immunodeficiency Virus), and helicobacter pylori [11,12,13] have been associated with susceptibility to ITP in several studies.…”