Research on Natural Phenolic Compounds in FAB-Lab: Nonconventional Industrial, Pharmaceutical, and Therapeutic Applications

Abstract

Phenolic compounds represent one of the secondary metabolites of plants with pharmaceutical and therapeutic applications. Flavonoids, quinones, bioflavonoids, neo-lignans, xanthones, curcuminoids, tannins, and coumarins are some examples of the major groups of commonly available phenolic compounds in our daily foods, beverages, and spices. From this standpoint, the Liver Research Laboratory (FAB Lab) at Mansoura university, Egypt, established a multidisciplinary research (chemistry, molecular biology, bioinformatics, pharmacology, and pharmaceutics) based on utilization of commonly abundant natural products from plants and agricultural wastes, especially phenolic compounds to meet the goal of applied scientific research in pharmaceutical industry, environment, public health, and to furnish a sustainable well-developed globe. Examples of our concerted efforts, for over 30 years, are in the area of natural products and utilization of environmental waste containing phenolic compounds for various health disorders (cancer, cataract, degenerative diseases, hyperpigmentation, hyperglycemia, skin disorders), nano-, green and click chemistry. This chapter presents a practical model from FAB-Lab to maximize the benefits from phenolic natural products that have not been optimally exploited to establish meaningful scientific applied research. Patents, innovations, and significant publications indexed by the Web of Science and Scopus databases in the journals that occupy the 1st and the 2nd quartile will be presented.

An Affordable and Efficient Graphite‐Coated Electrode for the Voltammetric Determination of Catechol

“…The conventional methods for determining phenolic compounds, including catechol, involve high-performance liquid chromatography, gas chromatography, electrochemical techniques, spectroscopic approaches, capillary electrophoresis, and liquid chromatography-mass spectrometry. [6] Among these techniques, the electrochemical ones emerge as highly advanta-geous, as they offer real-time analysis capabilities, enable direct detection without the need for intricate sample preparation, and are cost-effective, in contrast to the alternative methods. The latest advances in the electrochemical determination of phenols and catechol in particular are thoroughly explored in selected review articles.…”

Berry beverages: From bioactives to antidiabetes properties and beverage processing technology

“…(Badria & Blumenberg, 2022;Bittová et al, 2014;Criste et al, 2020;Guo et al, 2017b;Ilhan et al, 2021;Kallio et al, 2014;Korekar et al, 2014;Ma et al, 2016Ma et al, , 2022cMäättä et al, 2004;Mattila et al, 2006;Pop et al, 2013;Wang et al, 2022;Yang et al, 2016; Zader- nowski et al, 2005) Note: FW. The data review in this table are different in accuracy and unit of some active compounds due to different varieties, origins and processing technologies.…”