Reproduction performance and blood biochemical parameters in dairy cows: Relationship with oxidative stress status

Abstract

Background and Aim:During the last decades, reproduction performances declined dramatically worldwide, but little is known concerning the involvement of oxidative stress as a causative factor. Oxidative stress may act at different levels, with negative impacts on cell membrane integrity and other active molecules with potential subsequent effects on reproduction. The aim of the current study was to investigate the oxidative stress status in cows according to their reproductive performances.Materials and Methods:Peripheral blood concentration of two oxidative stress biomarkers, glutathione S-transferase (GST) and malondialdehyde (MDA), and other biochemical parameters (glucose, total lipids, cholesterol, triglycerides, albumin, total proteins, calcium, urea, creatinine, direct bilirubin, alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase) were determined in 40 healthy cows. Body condition score (BCS), calving to first service interval (FSI), calving to conception interval (CCI), and the number of service per conception (SPC) were simultaneously recorded for each cow.Results:Concerning FSI, three groups were established: Group 1 (from 44 to 60 days), Group 2 (from 60 to 70 days), and Group 3 (from 70 to 80 days). For CCI, two groups were considered: Group 1 (<110 days) and Group 2 (>110 days). MDA showed significant high values only in cows with the lowest BCS (1.5) compared to cows with BCS note of 2.5 and 3.5. No significant difference was observed in cows oxidative stress status (MDA and GST) according to reproductive performances (FSI, CCI, and SPC) in all studied groups.Conclusion:The results revealed relatively altered oxidative stress status in cows with abnormal reproductive performances; however, no significant difference was recorded whatever the considered reproductive parameter.

Assessment of Plasma Oxidative Stress Biomarkers and Metabolic Parameters of Dairy Heifers: Relationship with Success at First Service

“…It is often used as an indicator of membrane integrity and oxidative stress. The results found in our study were similar to those obtained by (Celi et al, 2012) and (Boudjellaba et al, 2018) in cows. In the same way in buffaloes, no significant differences were observed in mean MDA or NO values between females that presented oestrus but failed to conceive and those that did conceive (Amin et al, 2019).…”

Differentiation of Subclinical Ketosis and Liver Function Test Indices in Adipose Tissues Associated With Hyperketonemia in Postpartum Dairy Cattle

“…The peak of AST in ketosis cows was reached in 5 weeks postnatal, which was consistent with the change of BHBA. Because ALT and AST mainly reflect the damage of liver cells, AST, the exudative enzyme of liver cells, is usually used as a marker of liver fat deposition (46), it can be concluded that at this time, the damage of liver in ketosis cows is the most serious, and the abnormal change of liver function is the most prominent, but the average level of AST was higher (44). The ALT mainly exists in the cytoplasm of liver cells.…”

The impact of stress and selected environmental factors on cows’ reproduction

“…The reactive oxygen species express their adverse effects on disorders within the reproductive system through, among others, damage of genetic material of oocytes or endometrium damage. The results are the decrease in fertility and conception rate in cattle (Boudjellaba et al 2018). Furthermore, ROS destroys proteins and lipids in cells and provides for their apoptosis (Mavangira and Sordillo 2018).…”