Reproducibility of shear rate and shear stress assessment by means of ultrasound in the common carotid artery of young human males and females

Aim:To investigate the relationships among carotid wall shear stress (WSS), carotid intima-media thickness (IMT), and total plaque area (TPA) using ultrasound (US) in the common carotid artery (CCA) in patients with suspected coronary artery disease (CAD). Methods: Carotid artery US was performed in 950 patients with suspected CAD, and mean IMT, TPA, and hemodynamic parameters of CCA, including peak and mean WSS, were measured. We

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“…The inter-observer coefficients of variation for peak and mean WSS were between 6% and 8%, which were similar to a previous study 17) .…”

Section: ) Peak Wsssupporting

confidence: 74%

Low Carotid Artery Wall Shear Stress is Associated with Significant Coronary Artery Disease in Patients with Chest Pain

Cho

Kim

et al. 2016

J Atheroscler Thromb

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“…The time average diameter is computed from the diameter waveform obtained with a radio-frequency acquisition system [6]. Blood velocity profiles are estimated with a broadband (5-9 MHz) curved-array transducer, activated in a wide-band M-mode with a high pulse-repetition frequency of 10 kHz [31]. A cross-correlation function is applied to short radio frequency data segments to obtain blood flow velocities [5].…”

Section: Assessment Of Vessel Wall Distension and Maximum Velocity Wamentioning

confidence: 99%

Model-based assessment of dynamic arterial blood volume flow from ultrasound measurements

Leguy

Bosboom

Hoeks

et al. 2009

Med Biol Eng Comput

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To assess in clinical practice arterial blood volume flow (BVF) from ultrasound measurements, the assumption is commonly made that the velocity profile can be approximated by a quasi-static Poiseuille model. However, pulsatile flow behaviour is more accurately described by a Womersley model. No clinical studies have addressed the consequences on the estimated dynamics of the BVF when Poiseuille rather than Womersley models are used. The aim of this study is to determine the influence of assumed Poiseuille profile instead of Womersley profile on the estimation and intrasubject variability of dynamical parameters of the BVF. For this purpose, a low number of volunteers sufficed. Brachial artery centerline velocity waveform and vessel diameter were measured with ultrasound within a small group of six volunteers. Within subjects, the intra-and inter-registration variability of BVF parameters estimates did not significantly differ. Poiseuille profiles compared to Womersley underestimates the maximum BVF by 19%, the maximum retrograde volume flow by 32% and the rise time by 18%. It can be concluded that when estimating in a straight vessel the dynamic properties of the BVF, Womersley profiles should preferably be chosen.

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“…Several researchers have reported on blood flow rates measured on normal subjects in common carotid arteries (Reneman et al, 2006;Shaaban and Duerinckx, 2000;Gnasso et al, 1996;Hoeks et al, 1995;Oyre et al, 1998;Shamijo et al, 1997) and internal carotid arteries (Marshall et al, 2004;Deane and Markus, 1997). Flow waveforms have been characterized in common carotid arteries from DUS measurements (Holdsworth et al, 1999) and in internal carotid arteries and vertebral arteries from PC-MR measurements (Ford et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

Flow–area relationship in internal carotid and vertebral arteries

et al. 2008

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Subject-specific computational and experimental models of hemodynamics in cerebral aneurysms require the specification of physiologic flow conditions. Because patient-specific flow data is not always available, researchers have used "typical" or population average flow rates and waveforms. However, in order to be able to compare the magnitude of hemodynamic variables between different aneurysms or groups of aneurysms (e.g. ruptured vs. unruptured) it is necessary to scale the flow rates to the area of the inflow artery. In this work, a relationship between flow rates and vessel areas is derived from phase-contrast magnetic resonance measurements in the internal carotid arteries and vertebral arteries of normal subjects.

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Reproducibility of shear rate and shear stress assessment by means of ultrasound in the common carotid artery of young human males and females

Cited by 57 publications

References 10 publications

Low Carotid Artery Wall Shear Stress is Associated with Significant Coronary Artery Disease in Patients with Chest Pain

Low Carotid Artery Wall Shear Stress is Associated with Significant Coronary Artery Disease in Patients with Chest Pain

Model-based assessment of dynamic arterial blood volume flow from ultrasound measurements

Flow–area relationship in internal carotid and vertebral arteries

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