1998
DOI: 10.1097/00006842-199801000-00015
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Reproducibility of Mental Stress-Induced Myocardial Ischemia in the Psychophysiological Investigations of Myocardial Ischemia (PIMI)

Abstract: We conclude that two popular laboratory tests for mental stress-induced myocardial ischemia are modestly reproducible. The relatively low reproducibility is probably influenced by uncertainties in detecting relatively small changes in wall motion, habituation of the patient to repeated exposure to psychological stressors, and physiological differences in threshold for ischemia on different days of testing.

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Cited by 22 publications
(11 citation statements)
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“…Reproducibility of MSI was the focus of two early studies 2627 , and approaches that have the patient describe a previously emotionally upsetting event have demonstrated 90% reproducibility 26 .…”
Section: Moving Forwardmentioning
confidence: 99%
“…Reproducibility of MSI was the focus of two early studies 2627 , and approaches that have the patient describe a previously emotionally upsetting event have demonstrated 90% reproducibility 26 .…”
Section: Moving Forwardmentioning
confidence: 99%
“…For example, anger is associated with responses that promote ischemia or arterial occlusion, heart attacks, and arrhythmias (R Verrier & Mittelman 1996). Anxiety and bereavement are also associated with cardiac events, and stress appears to predispose cardiovascular disease or precipitate ischemic episodes, heart attacks, or other pathological states (Niedhammer et al 1998, Carney et al 1998. Presumably this occurs through a series of interrelated effects of stress or emotional arousal, including direct effects on the heart, on the vasculature, on blood flow and shear stress, and on the constituents of blood such as platelets (Ku 1997;Niebauer & Cooke 1996;Patterson et al 1994Patterson et al , 1995.…”
Section: Stress and Disease Processesmentioning
confidence: 99%
“…A rapidly growing body of research suggests that social stress, whether it is chronic or episodic, has deleterious effects on well-being (Ackerman et al, 2002;Benschop et al, 1998;Broadbent et al, 2003;Carney et al, 1998;Cesana et al, 2003;Cohen et al, 1999;Delahanty et al, 1996;Delahanty et al, 1997;Ironson et al, 1996 ;Pawlak et al, 2003;Stone et al, 1999). Studies of eventful stressors have focused on exposures to natural disasters such as a hurricane, or to traumas such as witnessing the aftermath of an airline crash (Ursano, 1997).…”
Section: Introductionmentioning
confidence: 99%