BACKGROUND: Good pain relief following caesarian section is of great importance and intrathecal opioids provide good quality postoperative analgesia for longer duration. So the following study describes a comparative study between intrathecal morphine and intrathecal buprenorphine for postoperative pain relief following caesarian section (CS) under subarachnoid blockade. AIMS:The study was conducted to compare intrathecal morphine and buprenorphine for post of analgesia following CS, to achieve analgesia without sedation for better maternal child bondage and to popularize intrathecal opioids. MATERIALS AND METHODS: 60 patients posted for CS under SAB were randomly allocated into group A and group B of 30 each, the group A received morphine 0.1 mg and buprenorphine 0.03 mg was given for group B patients along with the local anaesthetic. Subjective assessment of post-operative analgesia was done by direct questioning of the patient and by a five point pain scores. Duration of analgesia was taken as the time interval between the time of injection of intrathecal opiate and the time at which the patient felt pain and requested for additional analgesics. Data's were analyzed using SPSS 16th version. OBSERVATION AND RESULTS: The mean duration of post-operative analgesia with intrathecal morphine was 24.19+4.8 hours and that with buprenorphine was only 11.7+3.28 hours. Over weight patients reported a lower mean duration of analgesia. None of the patients in the study showed any bradycardia, hypotension, desaturation or respiratory depression. Intrathecal opiates decreased the parenteral opiate requirements. The main side effects noticed were nausea in about 43% of patients in morphine group and 33% of patients in buprenorphine group. CONCLUSIONS: Intrathecal morphine 0.1 mg gives good post-operative analgesia of longer duration than buprenorphine 0.03mg. The quality of analgesia provided by intrathecal morphine was superior to intrathecal buprenorphine. There was no incidence of respiratory depression or sedation.
BACKGROUND: Good pain relief following caesarian section is of great importance and intrathecal opioids provide good quality postoperative analgesia for longer duration. So the following study describes a comparative study between intrathecal morphine and intrathecal buprenorphine for postoperative pain relief following caesarian section (CS) under subarachnoid blockade. AIMS:The study was conducted to compare intrathecal morphine and buprenorphine for post of analgesia following CS, to achieve analgesia without sedation for better maternal child bondage and to popularize intrathecal opioids. MATERIALS AND METHODS: 60 patients posted for CS under SAB were randomly allocated into group A and group B of 30 each, the group A received morphine 0.1 mg and buprenorphine 0.03 mg was given for group B patients along with the local anaesthetic. Subjective assessment of post-operative analgesia was done by direct questioning of the patient and by a five point pain scores. Duration of analgesia was taken as the time interval between the time of injection of intrathecal opiate and the time at which the patient felt pain and requested for additional analgesics. Data's were analyzed using SPSS 16th version. OBSERVATION AND RESULTS: The mean duration of post-operative analgesia with intrathecal morphine was 24.19+4.8 hours and that with buprenorphine was only 11.7+3.28 hours. Over weight patients reported a lower mean duration of analgesia. None of the patients in the study showed any bradycardia, hypotension, desaturation or respiratory depression. Intrathecal opiates decreased the parenteral opiate requirements. The main side effects noticed were nausea in about 43% of patients in morphine group and 33% of patients in buprenorphine group. CONCLUSIONS: Intrathecal morphine 0.1 mg gives good post-operative analgesia of longer duration than buprenorphine 0.03mg. The quality of analgesia provided by intrathecal morphine was superior to intrathecal buprenorphine. There was no incidence of respiratory depression or sedation.
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