Repeatability of Noninvasive Keratograph 5M Measurements Associated With Contact Lens Wear

García-Montero, María; Rico-del-Viejo, Laura; Lorente‐Velázquez, Amalia; Martínez-Alberquilla, Irene; Hernández-Verdejo, José Luis; Madrid-Costa, David

doi:10.1097/icl.0000000000000596

Cited by 23 publications

(21 citation statements)

References 21 publications

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“…For the healthy eyes assessed in this study, the NIKBUTaverage was in concordance with NIKBUTaverage of 12.7 ± 6.5s reported by García-Montero et al [25], using Keratograph 5M in a healthy group of similar age range (26.3 ± 2.5 years). Tian et al…”

Section: Resultssupporting

confidence: 91%

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT)

Bandlitz¹,

Peter²,

Pflugi³

et al. 2019

Contact Lens and Anterior Eye

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Purpose: Since tear film stability can be affected by fluorescein, the International Dry Eye Workshop (DEWSII) recommended non-invasive measurement of tear breakup time (NIBUT). The aim of this study was to investigate the agreement and repeatability of four different instruments in the measurement of NIBUT.Methods: 72 participants (mean 24.2 ± 3.6 years) were recruited for this multi-centre, cross-sectional study. NIBUT was measured three times from one eye using each of the instruments in randomized order on two separate sessions during a day, separated by at least 2 hours. NIBUT was performed at three sites (Switzerland, Germany and UK) using the Tearscope Plus (Keeler, Windsor, UK) (TS), Polaris (bon Optic, Lübeck, Germany) (POL), EasyTear Viewplus (Easytear, Rovereto, Italy) (ET) and Keratograph 5M (Oculus Optikgeräte GmbH, Wetzlar, Germany) (KER). As the latter instrument only analyses for 24s, all data was capped at this value.Results: NIBUT measurements between the four instruments were not statistically

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Section: Resultssupporting

confidence: 91%

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT)

Bandlitz¹,

Peter²,

Pflugi³

et al. 2019

Contact Lens and Anterior Eye

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show abstract

“…Montero et al reported that repeatability of NIKBUT after wearing SCL decreases in comparison to that of before wearing SCL. 24 They also reported that NIKBUT was not significantly different among three types of silicon hydrogel contact lenses. 25 Mousavi et al reported that the evaluation of the prescribed SCL using conventional methods does not always correspond to the assessment of the tear film stability by NIKBUT.…”

Section: Introductionmentioning

confidence: 95%

<p>Comparison and Evaluation of Prelens Tear Film Stability by Different Noninvasive in vivo Methods</p>

Itokawa

Suzuki

Iwashita

et al. 2020

OPTH

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Purpose Prelens tear film stability of soft contact lens (SCL) play an important role for contact lens discomfort. In this study, we investigated the association between two types of noninvasive methods and evaluated the tear film stability with SCL using the methods. Patients and Methods In experiment 1, images of ring mire were recorded with a keratograph after focusing the pigment located at the front or back of the SCL. Interferometry and videokeratoscopy were used for the assessment of tear film stability in the right eye of 10 women, with two different cosmetic daily disposable SCLs: polymacon and etafilcon A with polyvinylpyrrolidone. Time to first distortion by noninvasive keratograph break up time (NIKBUT-first) was compared to noninvasive interferometry break up time (NIBUT). In experiment 2, ten normal females wore two different daily disposable SCLs: samfilcon A and narafilcon A. NIKBUT-first and NIBUT were compared between the lenses after 8 hours of SCL wearing. Results In experiment 1, NIBUT-first without SCL was significantly correlated to NIBUT without SCL (r=0.445, P=0.0488, Pearson’s correlation coefficients). However, NIKBUT-first with SCL was not significantly correlated with NIBUT with SCL. In experiment 2, although NIKBUT-first was not significantly different between SCLs, samfilcon A had significantly longer NIBUT than narafilcon A (P=0.0315, paired t -test). Conclusion NIKBUT-first with SCL could be related to tear film stability between the lens and the corneal surface, but not to prelens tear film stability. NIIBUT could be a suitable method to evaluate prelens tear stability.

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“…10 Video topography has been shown to objectively and reproducibly assess the in vivo pre-corneal tear film and the in vitro drying of contact lens surfaces. [11][12][13] Video topography involves the projection of ring mires onto the pre-corneal tear film and contact lens surfaces and the simultaneous recording of reflected images. 12 These technological advances allow examination of a larger area, covering more than the optical zone of a contact lens, as well as allowing subjective assessments.…”

Section: Introductionmentioning

confidence: 99%

<p>Subjective Comparison of Pre-Lens Tear Film Stability of Daily Disposable Contact Lenses Using Ring Mire Projection</p>

Müller¹,

Marx²,

Wittekind³

et al. 2020

OPTO

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Purpose: To subjectively evaluate the in vivo tear film stability of three daily disposable contact lenses (DDCLs) using placido ring reflection at lens wear times of 5 mins and 8 and 12 hrs. Patients and Methods: This prospective, randomized, observer-masked, 3-way crossover study evaluated 28 subjects with good tear film stability. In vivo tear film stability was assessed for three DDCLs (nelfilcon A, etafilcon A, omafilcon A) on three different days over 12 hrs of lens wear. Time to first distortion by non-invasive keratography drying-up time (NIK-DUT f) was assessed by reviewing the captured videos. Lens wettability was also graded subjectively by three investigators using a scale from 0 (no visible distortions) to 3 (distortions in more than one-third of the ring reflection zone). Medians were analyzed statistically. Results: Mean NIKDUT f at 8 hrs was longer for nelfilcon A and shorter for etafilcon A and omafilcon A, but the differences were not significant. NIK-DUT f did not differ significantly among nelfilcon A, etafilcon A and omafilcon A DDCLs at all visits (p=0.36). Subjective wettability grades after 5 mins, 8 hrs, and 12 hrs differed significantly for etafilcon A (P <0.01) and omafilcon A (p < 0.01), but not for nelfilcon A (p = 0.05), DDCLs. Conclusion: Grading was sufficiently sensitive to differentiate the wettability performances of the three lens materials. Nelfilcon A maintained wettability over the wearing period, whereas etafilcon A material showed faster dewetting at 8 and 12 hrs than at 5 mins after lens insertion.

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Repeatability of Noninvasive Keratograph 5M Measurements Associated With Contact Lens Wear

Cited by 23 publications

References 21 publications

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT)

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT)

<p>Comparison and Evaluation of Prelens Tear Film Stability by Different Noninvasive in vivo Methods</p>

<p>Subjective Comparison of Pre-Lens Tear Film Stability of Daily Disposable Contact Lenses Using Ring Mire Projection</p>

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