Repeatability and Reproducibility of Pachymetric Mapping with Visante Anterior Segment–Optical Coherence Tomography

Mohamed, Shaheeda; Lee, Gary K. Y.; Rao, Srinivas K; Wong, Alan C.-N.; Cheng, Arthur C.K.; Li, Emmy Y.M.; Stanley, Christina; Lam, Dennis S C

doi:10.1167/iovs.07-0591

Cited by 112 publications

(86 citation statements)

References 13 publications

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“…27 The definition of coefficient of repeatability was based on those adopted by the International Organization for Standardization. 28,29 The CR was defined as two standard deviations of the difference between two measurements. Pearson correlation coefficient (r) was used to describe the interclass correlation among graders.…”

Section: Methodsmentioning

confidence: 99%

Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

et al. 2012

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Abstract. This study is designed to test the repeatability of the quantitative analysis of intraretinal layer thickness and cup-disc ratio of the optic nerve head using ultra-high resolution optical coherence tomography (UHR-OCT). Group A, containing 23 eyes of 12 healthy subjects, was imaged twice and group B, containing eight eyes of four subjects, was imaged three times. Intraretinal layers were segmented manually and the cup-to-disc ratio of the optic nerve head was analyzed. Custom-built automatic segmentation software was also used to segment a set of images for comparison. A total of nine intraretinal layers were visualized and extracted manually. With group A, the central foveal thickness was 186.4 AE 15.9 μm (mean AE SD). The average retinal thickness was 296.4 AE 21.3 μm. The best repeatability, obtained when two repeated scans were taken, was obtained for the outer nuclear layer followed by the ganglion cell layer, the inner nuclear layer, the retinal nerve fiber layer and the worst was obtained for the outer segment. The intraclass correlation ranged from 0.824 to 0.997. The coefficients of repeatability ranged from 3.24 to 18.3 μm, corresponding to 1.47% to 26.20%. With group B, high interclass correlations were found and the automatic segmentation results were compatible with the manual results. Our results indicated that more retinal features might be imageable using UHR-OCT.

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Section: Methodsmentioning

confidence: 99%

Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

et al. 2012

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“…Coefficient of variation (COV): this was calculated as the within-subject SD of the three repeated measurements divided by the within-subject mean, and was expressed as a percentage. 8,31 Intra-session test-retest variability in RNFL thickness: this was measured in micrometres and was calculated as twice the SD of the three repeated measurements for each measure of RNFL thickness. 8 Differences between mean measurements before and after pupil dilation were assessed by a paired t-test.…”

Section: Statisticsmentioning

confidence: 99%

Effect of pupil dilation on retinal nerve fibre layer thickness measurements and their repeatability with Cirrus HD-OCT

Savini

Carbonelli²,

Parisi

et al. 2010

Eye

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“…A more recent study, with very similar results, describes as an interesting finding that IOP correlated directly with central corneal thickness and refraction, and inversely with the anteroposterior axis of the eye [5][6][7]. OCT has high reproducibility, and good correlation with ultrasonic pachymetry [8,9].…”

Section: Discussionmentioning

confidence: 84%

Juvenile glaucoma: Long-term development of ocular hypertension in children

M¹,

R²,

P³

et al. 2017

New Front Ophthalmol

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Aim: Study of the long-term development of children with treatment for ocular hypertension (OHT).Purpose: IOP development, to detect risk factors and clinical features in children with OHT. Method:A retrospective, descriptive and non-randomized study of 42 children treated for OHT, with a mean follow-up of 11.6 years.Results: Most common family history: glaucoma (58%) and myopia (23%). The most frequent systemic pathological history was of airways disease, related in many instances to the use of corticosteroids. The most prevalent refractive error was found to be myopia (55%). The most frequent reason for first time consultation was vision loss. The mean central corneal thickness found was 562 μm ± 41. The diagnosis of childhood glaucoma using campimetry is difficult, since it relies on patient cooperation. In most cases, optic disc assessment, both ophthalmoscopically and using OCT, was not found to be reliable. The mean age of suspected OHT is 11 years old, usually considering abnormal pressure above 18 mmHg, and initiating treatment at 22 mmHg. The mean decrease through topical hypotensive medication was 4.7 mmHg, with no significant adverse effects registered. Forty-six percent of children abandoned medical treatment, after several years of control, upon verifying that IOP was normal.Conclusions: Some children maintain high levels of IOP. Half of them will normalize their IOP around the age of 20, but others will maintain OHT being adults. The response to medical treatment was sufficient in all the cases.In the literature review, we did not find any series of children with OHT as extensive or over such a long period of time.

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Repeatability and Reproducibility of Pachymetric Mapping with Visante Anterior Segment–Optical Coherence Tomography

Abstract: With the pachymetric mapping protocol of Visante AS-OCT, these results suggest that central and peripheral corneal thickness measurements in healthy subjects and in eyes with keratoconus are repeatable and reproducible.

Cited by 112 publications

References 13 publications

Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

Effect of pupil dilation on retinal nerve fibre layer thickness measurements and their repeatability with Cirrus HD-OCT

Juvenile glaucoma: Long-term development of ocular hypertension in children

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