Repair of pig dura in vivo using temperature controlled CO₂ laser soldering

Abstract

It has been clearly demonstrated that temperature controlled laser soldering is a very useful technique for the repair of the dura. It provides significant advantages over standard closure techniques: it is easy to apply, the bond is strong and watertight and the procedure is likely to be much faster than suturing. This research work will lead to clinical trials.

Temperature-controlled optical stimulation of the rat prostate cavernous nerves

“…[20][21][22][23] The therapeutic window for successful laser tissue welding is relatively large (e.g., 50 to 100°C), allowing for significant error in temperature control without adverse thermal effects in the tissue. However, for the specific application of ONS, the therapeutic window for successfully activating the nerves is much narrower, thus representing a greater challenge.…”

In vitro large diameter bowel anastomosis using a temperature controlled laser tissue soldering system and albumin stent

“…Clinical and experimental use of lasers in bonding have been carried out on numerous types of tissues, including urinary tract [9,10], blood vessels [11], skin [12,13], and dura [14]. A variety of different techniques, lasers, solders and their parameters have been used in these studies.…”

Microscopic characterization of collagen modifications induced by low‐temperature diode‐laser welding of corneal tissue

“…Since then, for over 20 years several experiments have been carried out using a variety of lasers for sealing many tissue types, including that of blood vessels [2,3], urethra [4], nerves [5], dura mater [6,7], skin [8,9], stomach, [10] and colon [11].…”