Reovirus identified as cause of disease in young geese

Abstract

The pathology, epizootiology and aetiology of a specific disease of young geese, which has been seen in Hungary for more than three decades, were investigated. The disease was characterised by splenitis and hepatitis with miliary necrotic foci during the acute phase, and epicarditis, arthritis and tenosynovitis during the subacute/chronic phase. Clinical signs usually appeared at 2 to 3 weeks of age and persisted for 3 to 6 weeks. From different organs of the affected birds, a reovirus was isolated in embryonated eggs and tissue cultures of Muscovy duck or goose origin, as well as in Vero cells. In experimental infections, the dominant features of the disease were reproduced in day-old and young goslings. The biological and partial molecular characterisation of one of the isolated strains (D15/99) showed that it was related to the reovirus described as the cause of a similar disease of Muscovy ducks. An RT-PCR method suitable for the detection of reoviruses was also elaborated and tested. This is the first report on the involvement of reovirus in arthritis of geese.

Preparation and evaluation of goose reovirus inactivated vaccine

“…In 1972, Walke et al confirmed the virus as a “reovirus” [4]. Researchers subsequently identified ARV infection in South Africa, France, Israel, Italy, China, and many other countries [5–7]. In 1997, the main Muscovy duck breeding region in China was affected by an outbreak of duck reovirus (DRV) disease, which resulted in white spots on the liver.…”

“…It has been reported that GRV can cause viral arthritis in geese, and infected geese often exhibited spleen inflammation, while those with subacute or chronic onset showed pericarditis, arthritis, and/or tenosynovitis [7]. The GRV induced clinical symptoms appeared at 2–3 weeks of age, and the disease course lasted 3–6 weeks [11].…”

“…The GRV induced clinical symptoms appeared at 2–3 weeks of age, and the disease course lasted 3–6 weeks [11]. GRV has been isolated from various organs/tissues of infected geese [7]. A previous experiment showed that the virus strains from ducks and geese shared high homology in the S1 genome segment and [12] physico-chemical, clinical and biological characteristics and molecular properties were also identical to each other [7].…”

Genomic characterization of a turkey reovirus field strain by Next-Generation Sequencing

“…ARV affected poultry flocks commonly suffer from viral arthritis/tenosynovitis, enteric disease, immunosuppression, runting-stunting syndrome, and malabsorption syndrome (Sterner et al, 1989; van der Heide, 2000). Most domestic avian species are susceptible to ARV infections, such as broiler breeders (Ide and Dewitt, 1979), layer breeders (De Gussem et al, 2010), broilers (Howell and Walker, 1972), goose (Bezerra et al, 2012; Palya et al, 2003), turkey (Giangaspero et al, 1997; Taber et al, 1976), duck (Baroni et al, 1980; Petek et al, 1973; Rey et al, 1999), pigeon (Vindevogel et al, 1982), and quail(Guy et al, 1987; Magee et al, 1993; Ritter et al, 1986). However, the meat-type chickens are well documented species that are more susceptible to the viral arthritis/tenosynovitis caused by ARV than other avian species (De Gussem et al, 2010).…”

Induction of a robust immunity response against novel duck reovirus in ducklings using a subunit vaccine of sigma C protein

“…Avian orthoreovirus (ARV) is an important etiological agent that can cause several economically devastating diseases in a variety of domestic and wild birds, including chickens1, turkeys2, Muscovy ducks3, Pekin ducks4, geese56, wild mallard ducks7, pigeons8, psittacine birds9 and other wild birds. In waterfowl species, causative ARVs were first isolated in France in 1972 from Muscovy ducks, historically termed Muscovy duck reovirus (MDRV)3 and emerged in China in 199710.…”