Renal Tubular Necrosis and Papillary Necrosis after Gastroenteritis in Infants

Renal papillary necrosis in infancy.

“…The ultimate prognosis for children who survive the acute episode is uncertain. In two of the cases described by Chrispin et al (1970) IVUs 4 months after the initial illness did not show normal renal growth. A repeat IVU after 9 months in Case 2 of the present study showed normal renal growth.…”

“…5) (Stirling, 1958;Chrispin et al, 1970 (Kerr, 1968). This author also comments on the short oliguric phase in acute tubular necrosis in infancy; in our second case oliguria was present for only 3 days.…”

Renal Failure in the Newborn

“…Acute renal failure occurred in 7 per cent of all infants in the neonatal intensive care unit and was contributory in the death of 15 patients reported here. The complications included hyperkalemia ( 13), congestive heart failure (9) and massive edema (9). A summary of clinical findings is noted in Table 2.…”

Urographic Changes in Acute Papillary Necrosis in the Rat

“…The present study stems from finding urographic abnormalities in infants suffering acute renal damage following severe gastroenteritis (Chrispin et al, 1970). In these three patients intravenous urography revealed nephrograms that were abnormally persistent and prolonged selective opacification of the renal pyramids.…”