Renal Tubular Acidosis: An Uncommon Cause of Bad Obstetric History

Jain, Shweta; Sainarersh, Vellanki V.; Patel, Himanshu V.; Trivedi, Hargovind L

doi:10.1007/s13224-013-0440-0

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Theoretically, prolonged maternal metabolic acidosis due to chronic RTA impairs fetal growth and development and causes fetal distress, commonly resulting in preterm labor[ 11 ]. There has been a case of distal RTA secondary to possible Sjögren’s syndrome causing multiple pregnancy losses[ 7 , 13 ]. In this case, the patient had a history of preterm delivery of two babies without any congenital brain defects.…”

Section: Discussionmentioning

confidence: 99%

Incomplete distal renal tubular acidosis uncovered during pregnancy: A case report

Seong,

Kim,

Kim

et al. 2023

World J Clin Cases

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Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.

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Section: Discussionmentioning

confidence: 99%

Incomplete distal renal tubular acidosis uncovered during pregnancy: A case report

Seong,

Kim,

Kim

et al. 2023

World J Clin Cases

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“…RTA in pregnancy and the negative effects can be corrected, as seen in Firmin et al work, whenever the condition is diagnosed early and permanent damage has not yet occurred [ 2 ]. However, there have been cases, such as that of Jain et al, where RTA was found to be a cause of multiple loss of pregnancies in a 30-year-old patient [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Transient Proximal Renal Tubular Acidosis in Pregnancy

Narcisse

Agarwal

Kumar

2017

Case Reports in Nephrology

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Renal tubular acidosis (RTA) is a disorder that has improper function of renal acid-base regulation and is rarely encountered during pregnancy. Currently, there is no clear evidence on management and outcomes in patients with this condition. We report a case of a previously healthy 23-year-old female at 30 weeks of gestation who presented with proximal RTA and had spontaneous resolution of the condition shortly after delivery.

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Renal Tubular Acidosis: An Uncommon Cause of Bad Obstetric History

Cited by 2 publications

References 5 publications

Incomplete distal renal tubular acidosis uncovered during pregnancy: A case report

Incomplete distal renal tubular acidosis uncovered during pregnancy: A case report

A Rare Case of Transient Proximal Renal Tubular Acidosis in Pregnancy

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