Renal Transplantation in Cats with Chronic Renal Failure.

Survival, Complications, and Analysis of Risk Factors after Renal Transplantation in Cats

“…Available published data on transplant survival and the incidence of complications are limited. Few centers are performing RTr and therefore, most data originates from a single institution 1–10 . In a study of feline transplant recipients between 1987 and 1996, there was a 29% perioperative mortality and an estimated median survival, for those cats that survived to discharge but were dead at the time of analysis, of 12 months 2 .…”

“…Few centers are performing RTr and therefore, most data originates from a single institution. [1][2][3][4][5][6][7][8][9][10] In a study of feline transplant recipients between 1987 and 1996, there was a 29% perioperative mortality and an estimated median sur-vival, for those cats that survived to discharge but were dead at the time of analysis, of 12 months. 2 This group also reported 6-month and 3-year survival percentages for all cats that had RTr as 59% and 42%, respectively, for transplantations performed over the subsequent 3 years (1996-1999).…”

Ethical considerations in feline renal transplantation

“…Feline kidney transplantations have been performed since the 1980s for cats with CKD (Gregory, 1993;Mishina et al, 1996;Mathews and Gregory, 1997). Nevertheless, it remains a controversial treatment option and views on its acceptability differ among clinicians and countries.…”

Ureteral Papilla Implantation as a Technique for Neoureterocystostomy in Cats Undergoing Renal Transplantation: 30 Cases

“…Chronic kidney disease is a common diagnosis in domestic cats, with a reported incidence ranging from 4.5% to upward of 50% . Kidney transplantation is a well‐accepted treatment for end‐stage kidney disease with about 70% of cats surviving 1 year after surgery . Historically, neoureterocystostomy techniques have included the drop‐in technique, and intravesicular and extravesicular mucosal apposition techniques .…”

“…Historically, neoureterocystostomy techniques have included the drop‐in technique, and intravesicular and extravesicular mucosal apposition techniques . Although many advances have been made, complications associated with the neoureterocystostomy site are relatively common, including stricture, obstruction by granulation tissue, leakage, and dehiscence . The extremely small size of the normal feline ureter (∼0.4 mm luminal diameter) makes neoureterocystostomy using the transected end of the distal ureter technically very challenging and prone to postoperative complications.…”