Renal extramedullary haematopoiesis mimicking renal lymphoma on computed tomography

Galperin-Aizenberg, Maya; Volchek, Yulia; Sapir, Einav; Vasserman, Margarita; Maizlin, Zeev V.; Cohenpour, Mehrzad; Gayer, Gabriela

doi:10.1016/j.crad.2006.05.013

Cited by 10 publications

(5 citation statements)

References 12 publications

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“…In the perirenal type, the soft tissue encases both kidneys, such as in our Case 2. The bilateral perirenal localization of EMH may sometimes mimic a renal lymphoma [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…The differential diagnosis of a perirenal or parapelvic mass of uncertain aetiology includes tumours, lymphomas, lipomatosis and renal inflammatory or infectious tissue [ 2 , 6 ]. The role of nuclear medicine imaging or of FDG-PET/CT, to resolve such diagnostic problems, is still a controversial issue [ 6 ]. In both our cases, we chose a CT-guided biopsy approach to arrive at a final diagnosis.…”

Section: Discussionmentioning

confidence: 99%

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Extramedullary haematopoiesis in the kidney

Ricci¹,

Mandreoli²,

Valentino³

et al. 2012

Clinical Kidney Journal

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Extramedullary haematopoiesis (EMH) is the development of haematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare and there are very few case reports concerning the kidney. We describe two cases of ‘renal histologically documented EMH’ and, in particular, in the second of these two, the EMH tissue coexists with a clear cell renal carcinoma. Although rare, these clinical pictures raise some questions about the role of needle biopsy in the management of renal masses that present a diagnostic dilemma, especially in cases without involvement of other abdominal or intrathoracic organs.

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“…In the perirenal type, the soft tissue encases both kidneys, such as in our Case 2. The bilateral perirenal localization of EMH may sometimes mimic a renal lymphoma [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Extramedullary haematopoiesis in the kidney

Ricci¹,

Mandreoli²,

Valentino³

et al. 2012

Clinical Kidney Journal

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“…There are frequently multiple lesions, but this disease can manifest as a solitary lesion. Liver, spleen, and thoracic paravertebral regions are the most common sites of involvement (18). Renal extramedullary hematopoiesis is rare, with only a few reported cases.…”

Section: Figurementioning

confidence: 99%

“…The parapelvic type manifests as hypoattenuated hypovascular masses that encase the renal hila with distortion of the renal collecting systems. The perirenal type occurs as uniform enhancing masses either around (19) or encasing the kidneys (18). On CT, extramedullary hematopoiesis usually occurs as hypoenhancing lesions of soft-tissue attenuation due to its predominant hematopoietic component; however, fatty components have been reported (20).…”

Section: Figurementioning

confidence: 99%

Case 237: Renal Cell Carcinoma with Osseous Metaplasia

Lai¹,

Ka²,

Kan³

et al. 2017

Radiology

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History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia. Unenhanced and contrast-enhanced nephrographic phase CT was performed. Follow-up CT 3 months later showed minimal interval change in the lesion (images not shown).

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“…12). 24 At MRI, signal intensity on T2-weighted images is typically low owing to the hemosiderin content. At ultrasound, the perinephric lesions usually appear as solid hypoechoic masses.…”

Section: Infiltrative Lesionsmentioning

confidence: 99%