Renal disease in acute Plasmodium falciparum infection in man

Boonpucknavig, Vijitr; Sitprija, Visith

doi:10.1038/ki.1979.101

Cited by 99 publications

(52 citation statements)

References 44 publications

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“…Jaundice is the most common association with malarial ARF (MARF), occurring in more than 75% of cases 10 . ARF usually associated with intravascular hemolysis or heavy parasitaemia 11 .…”

Section: Introductionmentioning

confidence: 99%

Profile of Acute Kidney Injury in Plasmodium Vivax Malaria

Nigam¹

2017

JMSCR

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“…Jaundice is the most common association with malarial ARF (MARF), occurring in more than 75% of cases 10 . ARF usually associated with intravascular hemolysis or heavy parasitaemia 11 .…”

Section: Introductionmentioning

confidence: 99%

Profile of Acute Kidney Injury in Plasmodium Vivax Malaria

Nigam¹

2017

JMSCR

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“…It is characterized by severe proteinuria (Rees et al 1972; Rui-mei et al 1998b; Obgadoyi and Tembeng 1999, Sinnah et al 1999), rise in blood urea, low urine specific gravity, low ratio of urinary to blood urea ( Vanvelthuysen,1996) and hyper-kalaemia and metabolic acidosis (Mishra et al, 2002). ARF occurs in about 60% of all cases of complicated malaria (Boonpucknavig and Sitprija, 1979;Sitprija, 1988;Nanda et al, 2004). In Plasmodium falciparum malaria, ARF occurs in 1-5% of cases (Sheehy and Reba, 1967;Prakash et al, 1996;Naqvi et al, 2003) with mortality of 15-45% (Barsoum, 2000) Considering the endemicity of malaria in Nigeria, the mortality and morbidity rate across families, particularly in children and pregnant women, accurate prognosis and proper management are very necessary.…”

Section: Introductionmentioning

confidence: 99%

Assessment Of Renal Function In Malaria Patients In Minna, North Central Nigeria

Ogbadoyi¹,

Gabi²

2008

African Journal of Infectious Diseases

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Establishment of prevalence of malaria-associated renal impairment in Nigeria is important for proper prognosis and management of malaria and its associated complications. Using biuret method for protein estimation, alkaline picrate-slot method for creatinine and urea estimation, and flame photometry and titrimetric method for electrolytes estimation, selected kidney function parameters which included proteinuria, serum levels of urea, creatinine and electrolytes were determined in 169 malaria patients and in 58 individuals without malaria. Data obtained were analyzed using one-way analysis of variance to compare variation among malaria patients and individuals without malaria, Duncan multiple range test to compare variation among means, and correlation matrix to evaluate correlation between the parameters measured. Proteinuria in malaria cases differed significantly (p< 0.05) from individuals without malaria, and a positive correlation existed between proteinuria and parasitaemia. There was no significant difference (p>0.05) in the creatinine levels of malaria patients and those without malaria. It is concluded that there is a form of renal impairment associated with malaria infection in Minna irrespective of age and sex.

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“…Acute renal failure (ARF) is a serious complication whose incidence is less than one percent among all cases of falciparum malaria, but occurs in about sixty percent of complicated cases (1,2). The malaria parasite has been shown to generate abnormally large quantities of reactive oxygen species (ROS) within the infected erythrocytes (3).…”

Section: Introductionmentioning

confidence: 99%

Evaluating role of oxidative stress in determining the pathogenesis of falciparum malaria induced acute renal failure

Nanda

Mishra

Das

et al. 2004

Indian J Clin Biochem

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Serum malondialdehyde was measured in sixty-one falciparum malaria cases, which include thirty uncomplicated, and thirty-one complicated with acute renal failure. Twenty-six healthy individuals were also studied as controls. Serum malondialdehyde level was found to be significantly elevated in falciparum malaria induced acute renal failure cases when compared with uncomplicated falciparum malaria (p<0.001) and healthy controls (p<0.001). A positive correlation with the raised urea, creatinine and bilirubin levels were significant (r=0. 62, p<0.025; r=0.65, p<0.05 and r=0.72, p<0.001 respectively) indicating the severity of complication with rise of lipid peroxides in falciparum malaria induced acute renal failure cases.

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Renal disease in acute Plasmodium falciparum infection in man

Cited by 99 publications

References 44 publications

Profile of Acute Kidney Injury in Plasmodium Vivax Malaria

Profile of Acute Kidney Injury in Plasmodium Vivax Malaria

Assessment Of Renal Function In Malaria Patients In Minna, North Central Nigeria

Evaluating role of oxidative stress in determining the pathogenesis of falciparum malaria induced acute renal failure

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