Renal cell carcinoma: vena caval involvement

Boorjian, Stephen A.; Sengupta, Shamik; Blute, Michael L.

doi:10.1111/j.1464-410x.2007.06826.x

Cited by 97 publications

(83 citation statements)

References 32 publications

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“…This probably reflects the increased technical difficulty and complication rates of caval thrombectomy with more extensive VTT. One large study reported a step-wise increase in early complication rates from 12% in those with renal vein thrombus to 47% in those with right atrial thrombus [15]. Additionally, surgical blood loss is significantly greater in patients with a greater extent of VTT [15].…”

Section: Discussionmentioning

confidence: 99%

“…One large study reported a step-wise increase in early complication rates from 12% in those with renal vein thrombus to 47% in those with right atrial thrombus [15]. Additionally, surgical blood loss is significantly greater in patients with a greater extent of VTT [15]. Finally, surgery involving cardiopulmonary [16] or veno-venous bypass [17] is probably more intimidating from both the patient's and the physician's perspective, and may dissuade them from pursuing surgical management.…”

Section: Discussionmentioning

confidence: 99%

“…'Rx Surgery Primary Site 1998 + ' was used to identify the type of surgery as follows: no surgery (0), ablation (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25), partial nephrectomy (26-39), radical nephrectomy (40-89), nephrectomy not otherwise specified (90) and unknown (99). Patients undergoing no surgery or ablation were combined into a no surgery group, whereas patients treated with partial nephrectomy, radical nephrectomy or nephrectomy not otherwise specified were combined into a surgery group.…”

Section: Methodsmentioning

confidence: 99%

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Factors associated with surgery in patients with renal cell carcinoma and venous tumor thrombus

2010

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• Univariable and multivariable logistic regression analysis was performed to identify factors associated with surgery. RESULTS• We identified 24 396 patients with RCC, of which 2265 (9.3%) had venous tumour thrombus.• CONCLUSIONS• In this population-based study, over 80% of patients with RCC and venous tumour thrombus underwent surgical management.• Although age and TNM stage were strongly associated with the decision to undergo surgery, marital status was also associated with treatment choice.• It is unclear whether marital status affects oncological outcomes or complication rates so the reasons behind this association deserve further investigation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Factors associated with surgery in patients with renal cell carcinoma and venous tumor thrombus

2010

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“…Patients with incomplete resections (excluding patients with metastatic disease) have a significantly worse prognosis, a finding that reflects the importance of surgical eradication of disease [4]. Hatcher noted that the prognosis was determined by the ability to perform a complete resection of the tumor, not by the level of tumor thrombus [40,49].…”

Section: Prognosismentioning

confidence: 99%

IVC Thrombectomy in Renal Cell Carcinoma—Analysis of Out Come Data of 100 Patients and Review of Literature

Kulkarni

Jadhav

Valsangkar

2011

Indian J Surg Oncol

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To review our experience of RCC with IVC thrombus in terms of clinical presentation, principles of surgical management in contemporary era, also an impact of clinico-pathological factors on prognosis. Total 100 patients who underwent radical nephrectomy and IVC thrombectomy between 1991-2008 were included in this retrospective analysis. Data was analysed in terms of clinical pathological factors, survivals and compared with contemporary literature. The extent tumour thrombus was infrahepatic in 58 retro hepatic in 28 and suprahepatic in 14 patients including 6 with right atrial thrombus. The immediate postoperative mortality was 2% and incidence of major postoperative non fatal complications was 38%, which were managed conservatively. The overall and disease free 5 year survival was 63% and 55%. Further amongst the histological types, patients with clear cell tumours had the best (DFS-71.42%), and those with papillary had the poor (DFS-30.76%) outcome. Grade II tumors had better survivals as compared to grade IV (DFS 75.39% vs 23.52%, p<0.05). Loco-regional extent wise 74% patients without perinephric fat invasion were free from disease at 5 years as compared to 30% of those who had perinephric fat invasion (p<0.01). Similarly 5 year DFS was 76.11% in patients with negative nodes as compared to 12% in positive nodes (p<0.01). In conclusion radical nephrectomy with IVC thrombectomy still remains the most effective therapeutic option in management in this clinical setting. Although this is complicated surgery success with multi disciplinary approach excellent survival outcome can be obtained. Further pathological factors, such as locoregional spread and grade of tumor, rather than clinical factors influence long term survival.

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“…Лечение больных ПКР, осложненным опухоле-вым тромбозом НПВ, до сих пор остается сложной задачей [13][14][15][16][17][18][19]. Крайне важным для безопасного удаления тромбов НПВ является дооперационная топическая диагностика опухолевого тромба: его протяженность и размеры, наличие инвазии в стен-ку вены, состояние печеночных вен (наличие синд-рома Бадда-Киари), размеры и мобильность интра-вентрикулярного компонента тромба, наличие и протяженность кровяного компонента тромба, особенно ретроградного, наличие коллатералей и степень их выраженности.…”

Section: Introductionunclassified

Surgical treatment of kidney cancer with extended inferior vena cava thrombosis: complications and long-term results

Атдуев¹,

Амоев²,

Danilov³

et al. 2017

Cancer Urology

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Контакты: Зураб Владимирович Амоев amoev_82@mail.ru Цель исследования -анализ факторов, влияющих на результаты тромбэктомии из нижней полой вены (НПВ) при почечно-кле-точном раке. Материалы и методы. Нефрэктомия с тромбэктомией из НПВ произведена 53 больным (31 (58,5 %) мужчине и 22 (41,5 %) женщинам) с протяженными тромбами. Возраст пациентов составлял 35-76 лет (средний возраст 58,7 ± 10,1 года). У 36 (68 %) больных была установлена стадия Т3b (протяженность тромба в среднем -5,28 ± 0,32 см), у 17 (32 %) пациентов -стадия Т3с (13,00 ± 0,71 см

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Renal cell carcinoma: vena caval involvement

Cited by 97 publications

References 32 publications

Factors associated with surgery in patients with renal cell carcinoma and venous tumor thrombus

Factors associated with surgery in patients with renal cell carcinoma and venous tumor thrombus

IVC Thrombectomy in Renal Cell Carcinoma—Analysis of Out Come Data of 100 Patients and Review of Literature

Surgical treatment of kidney cancer with extended inferior vena cava thrombosis: complications and long-term results

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