Renal cell carcinoma metastasis to the ovary: a case report

Clinical Spectrum of Patients with Renal Cell Carcinoma

“…Toquero L et al reported a case of 54-year old woman with a pelvic mass as an initial presentation of RCC. The mass was actually ovarian metastasis from RCC (Toquero et al, 2009).Ovarian metastases usually originate from stomach, colon, breast cancers and lymphoma. However, RCC needs to be considered in differential diagnosis.…”

Renal Cell Carcinoma Metastatic to the Ovary

“…One theory highlights the unique anatomy of the left renal and ovarian veins, attributing metastasis to the ovaries to hematogenous dissemination via retrograde venous emboli through the renal vein to the ovarian veins. 3,7 This theory is supported by the fact that most of the reported cases of ovarian metastasis occurred from a left renal neoplasm. 3,7 Whether epidemiological factors also have a role in the mechanism of metastasis is uncertain, as RCC more commonly affects men and postmenopausal women.…”

“…3,7 This theory is supported by the fact that most of the reported cases of ovarian metastasis occurred from a left renal neoplasm. 3,7 Whether epidemiological factors also have a role in the mechanism of metastasis is uncertain, as RCC more commonly affects men and postmenopausal women. 3,7 There are no specific radiological findings to differentiate between primary and metastatic ovarian lesions.…”

“…6 Extragenital metastases to the ovaries are rare and frequently mistaken for a primary ovarian neoplasm. 3,5,7 Frequency rates of primary tumors that metastasize to the ovaries vary among populations and studies. 8 The incidence of metastasis to the ovaries from any primary cancer is difficult to estimate but incidence rates of 7% to 12.5% have been reported.…”

“…8 Patients with ovarian metastasis may present with such nonspecific symptoms as bloating, abdominal pain, nausea, vomiting and weight loss years before the primary tumor is detected. 3,5,7,8 There is no clear consensus as to the mechanism of metastasis to the ovaries from RCC. One theory highlights the unique anatomy of the left renal and ovarian veins, attributing metastasis to the ovaries to hematogenous dissemination via retrograde venous emboli through the renal vein to the ovarian veins.…”