“…So far, extensive studies have been conducted on the occurrence of antibiotics in the influent and effluent of WWTPs (Gulkowska et al, 2008;Karthikeyan and Meyer, 2006;Zorita et al, 2009), while only limited information was available on the occurrence and distribution patterns of antibiotics in sludge mainly due to its high complex matrix (Jelic et al, 2011;Kümmerer, 2009). It was reported that the concentrations of antibiotics ranged from μg/kg to a few mg/kg in sewage sludge from different countries, such as Estonian (Lillenberg et al, 2009), Italy (Zuccato et al, 2010), Spain (Nieto et al, 2010;Radjenović et al, 2009), Switzerland (Göbel et al, 2005), USA (Kinney et al, 2006), Japan (Okuda et al, 2009) and China (Xu et al, 2007).…”