Remission of Ulcerated Necrobiosis Lipoidica Diabeticorum after Bariatric Surgery

Abstract

A 32-year-old woman with type 2 diabetes mellitus suffering from morbid obesity with BMI 45,14 kg/m2 was operated on. Not only the type 2DM but also one of its complication known as necrobiosis lipoidica diabeticorum remitted postoperatively. Obesity should no longer be regarded simply as a cosmetic problem affecting certain individuals but an epidemic that threatens global well-being. It causes or exacerbates many health problems, and in particular, it is associated with the type 2 diabetes. Necrobiosis lipoidica is a granulomatous skin disease of unknown etiology, associated mainly with diabetes mellitus. We presented in this paper a morbid obese case of necrobiosis lipoidica diabeticorum with dramatic good response to bariatric surgery.

Cofactors and comorbidities of necrobiosis lipoidica: analysis of the German DRG data from 2012

“…With respect to the aforementioned aspects of the specific adipophilin expression pattern, obesity and hyperlipidemia – both linked to lipid accumulation – might thus be associated with NL. There has also been a case report describing the remission of ulcerated NL following bariatric surgery in a morbidly obese patient . Analysis of our patient population also suggests cardiovascular diagnoses such as chronic heart failure (4.1 %) or atherosclerosis (1.9 %) as additional potential risk factors.…”

Bariatric surgery – a dermatologic perspective

“…Bozkurt et al . reported on a 32‐year‐old woman with diabetes mellitus type 2 and ulcerated necrobiosis lipoidica who, after BS, achieved a complete remission of her skin disease and of diabetes …”

Does weight loss lead to improvement of dermatological conditions: what is the evidence?

“…Weight loss can improve various conditions seen in association with diabetes mellitus and MetS, such as AN and necrobiosis lipoidica 63 . These changes are reported to be more directly related to improved glycaemic control 64 …”