Remineralizing potential of a 60‐s <i>in vitro</i> application of Tooth Mousse Plus

Gopalakrishnan, Vaishnavi; Anthonappa, Robert P.; King, Nigel M.; Itthagarun, Anut

doi:10.1111/ipd.12268

Cited by 8 publications

(7 citation statements)

References 24 publications

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“…A lack of an additional benefit was noted when the fluoridated dentifrice was combined with TMP in Group F (1000ppm F + TMP) which is consistent with previous studies 11,21 . Numerous authors [18][19][20]22,23 have supported the need for a constant low level of F for remineralization rather than an acute exposure to a high level of F. It has been postulated that the F deposition occurs primarily in the surface layer, leading to blockage of the surface layer pores.…”

Section: Discussionsupporting

confidence: 90%

Remineralizing Potential of Clinpro® and Tooth Mousse Plus® on Artificial Carious Lesions

Buckshey

Anthonappa

King

et al. 2019

Journal of Clinical Pediatric Dentistry

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Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro ® Tooth Crème(CTC) and Tooth Mousse Plus ® (TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Posttreatment maximum mineral content at the surface zone(Vmax) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.

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Section: Discussionsupporting

confidence: 90%

Remineralizing Potential of Clinpro® and Tooth Mousse Plus® on Artificial Carious Lesions

Buckshey

Anthonappa

King

et al. 2019

Journal of Clinical Pediatric Dentistry

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“…In this study, enamel surface was artificially demineralized using an acidic solution (2.2mM CaCl 2 , 2.2mM KH 2 PO 4, 0.05M Acetic acid, pH adjusted to 4.4 1M KOH). 10 The reason for selecting artificially demineralized enamel was to assess the staining property of SDF when used as a preventive agent in arresting incipient carious lesions.…”

Section: Discussionmentioning

confidence: 99%

“…The teeth were immersed in a demineralizing solution (2.2mM CaCl 2 , 2.2mM KH 2 PO 4, 0.05M Acetic acid, pH adjusted to 4.4 1M KOH) for 96 hours. 10 ml of the demineralizing solution was used per sample [10] . After sample preparation, baseline colour measurements (T 0 ) were taken of all the samples with the help of a UV-Vis spectrophotometer.…”

Section: Sample Preparationmentioning

confidence: 99%

A comparative analysis of staining propensity of SDF, SDF with potassium iodide and SDF with glutathione biomolecule on demineralized enamel: An in-vitro study

Gupte¹,

Saraf²,

Jawdekar³

et al. 2021

Int. J. Appl. Dent. Sci.

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To evaluate and compare the staining propensity of SDF, SDF with Potassium iodide and SDF + Glutathione biomolecule on demineralized enamel. Study Design: Forty-five teeth were selected and stratified to receive either 38% SDF; 38% SDF + KI or 38% SDF + 20% GSH. The analysis for staining (E) was done using a UV-Vis Spectrophotometer and was recorded at different intervals for one month. Data analysis was done using Kruskal-Wallis test, Post-hoc analysis (Dunn) and a repeat-measures analysis of variance (RM-ANOVA). Results: SDF caused maximum staining. SDF + KI staining was significantly less (P<0.05) compared to SDF at 1 week, 2 weeks and one month. SDF + GSH showed least staining at 5 minutes and 24 hours among the three groups but the staining increased gradually and had no statistical difference after 1 week, 2 weeks and one month when compared to other groups. Conclusion: Application of KI following SDF helps in reducing the staining. Addition of GSH had no significant effect.

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“…Multiple studies [16,17] have utilized 4-day cycles for enamel demineralization which were proven to be a predictable and reliable protocol, hence it was decided to re-evaluate lesions seen after every 4 days to reduce cost and time consumed. During the demineralizing process, 4 days was adequate to create lesions in lactic acid buffer while 8 days was required in the acetic acid buffer solution to create reliable lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Two demineralizing solutions (acetic acid buffer and lactic acid buffer) were prepared. Acetic acid buffer contained 2.2 mM CaCl 2 , 2.2 mM KH 2 PO 4 and 0.05 M acetic acid adjusted with 5 M KOH to pH 4.4 [16]. Lactic acid buffer solution contained 0.1 M 85% lactic acid, 0.16 mM Ca(H 2 PO 4 ) 2 diluted to 1 L of distilled water (DIW) and adjusted with 1 M KOH to a pH of 4.4 [17].…”

Section: Specimen Preparationmentioning

confidence: 99%

A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel

et al. 2023

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Purpose: To investigate the mineral density and lesion depth of artificial caries lesions on aprismatic enamel and prismatic enamel created by lactic acid and acetic acid buffers. Methods: Forty bovine enamel blocks were allocated to: aprismatic enamel (Group A) and prismatic enamel (Group C) in acetic acid buffer for 192 h and aprismatic enamel (Group B) and prismatic enamel (Group D) in lactic acid buffer for 96 h. The mineral loss and lesion depth were measured using micro-computed tomography. Results: A significant difference (P = 0.01) was observed in the mineral loss (%) in the lesions on aprismatic enamel and prismatic enamel treated with lactic acid buffer while no significant difference (P = 0.51) was observed in the mineral loss (%) in the lesions on aprismatic enamel and prismatic enamel treated with acetic acid buffer. No significant difference was noted in the mean lesion depth of lesions on aprismatic enamel and prismatic enamel treated with acetic acid and lactic acid buffers (P > 0.05). Conclusion: Aprismatic enamel and prismatic enamel have similar mineral loss in acetic acid while prismatic enamel showed more mineral loss compared to aprismatic enamel in lactic acid.

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Remineralizing potential of a 60‐s in vitro application of Tooth Mousse Plus

Abstract: TMP applied for 60 s significantly remineralized the artificial carious lesions. No additional benefit was evident when TMP was preceded by treatment with 1000 ppm F dentifrice.

Cited by 8 publications

References 24 publications

Remineralizing Potential of Clinpro® and Tooth Mousse Plus® on Artificial Carious Lesions

Remineralizing Potential of Clinpro® and Tooth Mousse Plus® on Artificial Carious Lesions

A comparative analysis of staining propensity of SDF, SDF with potassium iodide and SDF with glutathione biomolecule on demineralized enamel: An in-vitro study

A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel

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