Remifentanil- and Fentanyl-Based Anesthesia for Intraoperative Monitoring of Somatosensory Evoked Potentials

Samra, Satwant K.; Dy, Eric A.; Welch, Kathleen B.; Lovely, Lisa K.; Graziano, Gregory P.

doi:10.1097/00000539-200106000-00031

Cited by 44 publications

(24 citation statements)

References 11 publications

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“…Remifentanil was chosen as the analgesic because its short half-life permits rapid establishment of a stable blood concentration. However, remifentanil does have a slight suppressive effect on SEPs (21,22), and this effect cannot be quantified in our study. To minimize this effect in our study, the smallest dose that abolished the motor response to tail clamp was determined for each rat, and this infusion rate was maintained throughout the experiment.…”

Section: Discussionmentioning

confidence: 60%

Preservation of the Cortical Somatosensory-Evoked Potential During Dexmedetomidine Infusion in Rats

Lohmann

Schuler

et al. 2003

Anesthesia & Analgesia

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Section: Discussionmentioning

confidence: 60%

Preservation of the Cortical Somatosensory-Evoked Potential During Dexmedetomidine Infusion in Rats

Lohmann

Schuler

et al. 2003

Anesthesia & Analgesia

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“…When compared with the recovery profile of fentanyl, it is reported that remifentanil group shows early recovery. [19]…”

Section: Discussionmentioning

confidence: 99%

Remifentanil infusion as a modality for opioid-based anaesthesia in paediatric practice

2010

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This study was designed to compare the intra-operative and post-operative analgesic requirements and side effects of using fentanyl infusion versus remifentanil infusion during short-duration surgical procedures in children. The study comprised of 40 children randomly allocated into two equal groups: fentanyl (F-group) or remifentanil (R-group). Both were administered a continuous intravenous (i.v.) infusion. Anaesthetic recovery was assessed using the Brussels sedation scale every 5 min from the time of entry till discharge from recovery room. Post-operative analgesia was assessed throughout the first three post-operative (PO) hours using observational pain–discomfort scale (OPS) and adverse events were recorded. Haemodynamic variables showed a non-significant difference between both the groups. Patients who received remifentanil showed significantly shorter time to spontaneous respiration, eye opening, extubation and verbalization compared to those who received fentanyl. Discharge time was significantly shorter in R-group, and 18 patients fulfilled criteria for recovery-room discharge at ≤25 min with a significant difference in favour of remifentanil. Fentanyl provided significantly better PO analgesia than remifentanil and children in F-group showed a significantly lower mean cumulative OPS record than those in R-group; however, the number of patients requiring rescue analgesia did not show a significant difference between both the groups. Two cases in F-group and one in R-group had bradycardia, one case in R-group had mild hypotension and PO vomiting had occurred in three patients in the F-group and two patients in the R-group. In conclusion, remifentanil is appropriate for opioid-based anaesthesia for paediatric patients as it provides haemodynamic stability and rapid recovery with minimal post-operative side effects.

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“…In addition to its analgesic property, its quick titratability makes early neurological examination possible (14). Importantly, it does not adversely affect neurological monitoring in the clinical doses used (18,19). Clinically, it appears to possess sympatholytic property because it typically decreases heart rate and reduces the fluctuation of blood pressure.…”

Section: Drugs To Maintain Anesthesia: Which and Whymentioning

confidence: 99%

Practice Trends and Research Priorities of Neurosurgical Anesthesia

Meng¹,

Li²,

Gelb³

2015

J Anesth Perioper Med

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Aim of review:One of the goals of neurosurgical anesthesia is to facilitate the execution of neurosurgical procedures including intraoperative neurological monitoring. However, it should also and always aim at benefiting the patients by improving the patient's long-term and disease-specific outcomes. Method: In this review, we highlighted some perspectives of today's practice trends and research priorities of neurosurgical anesthesia for the purpose of exploring the best care based on evidence, and speculation where relevant evidence is lacking. Recent findings: The advancement in general anesthesia and better understanding of neurological diseases have promoted the evolution of the sub-specialty of neurosurgical anesthesia. Facilitating modern neurosurgical procedures including intraoperative neurological monitoring is a priority of neurosurgical anesthesia. However, a focus on the patient outcomes can never be over-emphasized. The effect of any component of anesthesia care, such as drugs choice and dose, ventilation management, and intravascular volume and cardiac output care, on patient's outcome should be appraised by quality research. Summary: It is important to recognize that different patient populations have different and disease/surgery-specific outcomes that should also be taken into account during the customization of anesthesia techniques. ABSTRACT

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Remifentanil- and Fentanyl-Based Anesthesia for Intraoperative Monitoring of Somatosensory Evoked Potentials

Cited by 44 publications

References 11 publications

Preservation of the Cortical Somatosensory-Evoked Potential During Dexmedetomidine Infusion in Rats

Preservation of the Cortical Somatosensory-Evoked Potential During Dexmedetomidine Infusion in Rats

Remifentanil infusion as a modality for opioid-based anaesthesia in paediatric practice

Practice Trends and Research Priorities of Neurosurgical Anesthesia

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