Reliability Study of the Liquid Target Chamber for &lt;sup&gt;18&lt;/sup&gt;F Production at the BATAN’s Cyclotron Facilities

Kambali, Imam; Heryanto, T.; Rajiman, Rajiman; Ichwan, S.

doi:10.17146/aij.2011.69

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Sm, 211 At, and 177 Lu have been conducted  Corresponding author. E-mail address: maiyesni@yahoo.com DOI: https://doi.org/10.17146/aij.2019.930 theoretically and experimentally [13][14][15][16][17][18][19][20][21]. Apart from cyclotron-based radionuclide production, nuclear reactor-based radioisotope production has also been studied elsewhere, including for production of diagnostic and therapeutic radioisotope such as beta-emitting radioisotopes 131 I and 153 Sm [22,23].…”

Section: Introduction mentioning

confidence: 99%

Spectral Comparison of Neutron-Irradiated Natural and Enriched Ytterbium Targets for Lu-177 Production

et al. 2019

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Beta-emitting radioisotope 177 Lu has been suggested for radioimmunotherapy, peptide receptor radionuclide therapy, or another radionuclide therapy due to its excellent properties for destroying cancer cells. In this experimental investigation, natural ytterbium ( nat Yb) and enriched 176 Yb targets were irradiated with thermal neutrons at 1.2×10 14 cm -2 s -1 neutron flux for 95 hours. Using a high-purity germanium (HPGe) detector-based spectroscopy system, the post-irradiated targets were measured and the produced radioisotopes were identified according to their gamma ray emissions. Experimental results indicated that several radioisotopes such as 169 Yb and 175 Yb dominate the post-irradiated nat Yb target, though a relatively weak intensity of 177 Lu was also recorded. In contrast, 177 Lu radioisotope dominates the gamma rays observed in the post-irradiated enriched 176 Yb target following elution with HNO 3 solution. For the first time, evidence is found of 175 Yb impurity in the post-neutron-irradiated enriched 176 Yb 2 O 3 target as a result of 176 Yb(n,2n) 175 Yb nuclear reaction. This work recommends future 177 Lu radioisotope production using enriched 176 Yb 2 O 3 target.

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Section: Introduction mentioning

confidence: 99%

Spectral Comparison of Neutron-Irradiated Natural and Enriched Ytterbium Targets for Lu-177 Production

et al. 2019

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“…BATAN's CS-30 cyclotron is a circular accelerator that accelerates energetic protons to up to 26.5 MeV. The proton beam is then employed in producing medical radionuclides such as Cu-64 and F-18 [1,2] as well as in other research related to materials analysis such as thin layer activation analysis (TLA) and ultrathin layer activation (UTLA) techniques [3,4].…”

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Identification and Angular Distribution of Residual Radionuclides Detected on the Wall of BATAN’s Cyclotron Cave

2016

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Detection and measurement of radiation sources around BATAN's cyclotron facilities in Serpong are required as an early step to avoid radiation impacts on the radiation employees who work with the cyclotron. In this paper, radiation emitted from the wall of the CS-30 cyclotron cave are detected and measured using an NaI(Tl) detector coupled with a pocket multichannel analyzer (MCA) at a counting time of 30 minutes for each sampling point on the wall. The sampling points were in the directions of within ±150 o with respect to the incoming proton beams, and the measurements were conducted at heights between 1.2 m and 1.8 m off the floor for every sampling point. The experimental results indicate that Co-60 and Cs-134 detected on the cyclotron cave wall are major radionuclides that contribute to the emitted gamma radiation. The distribution of the gamma ray intensities given off by Co-60 and Cs-134 depend on the angle and position of the sampling points. In general the highest gamma ray rates can be found in the area around 0 o relative to the incoming proton beams. In addition, no other radioactive sources are significantly detected on the wall. The maximum exposure measured on the wall surface was much less than the permissible occupational exposure for radiation workers and general public.

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Theoretical study on production of stable and radioactive isotopes from proton irradiated sodium chloride

Kambali

2020

J. Phys.: Conf. Ser.

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The search for new radioactive isotopes has been on the rise due to high demands of positron-emitting radionuclides applicable for positron emission tomography (PET) modality in nuclear medicine. In this investigation, proton irradiations of sodium chloride (NaCl) were theoretically highlighted, including discussion on stable and radioactive isotopes produced during proton bombardment of the NaCl target. TALYS 2015-Calculated results indicated that 23Mg, 20Ne, 32S, 35Ar, 37Ar and 34S were expectedly produced following NaCl irradiation with 11 MeV protons. More isotopes such as 22Na, 34mCl, 36Cl and 36Ar were generated when the proton energy was increased to 26.5 MeV. Positron emitting radionuclides were found to dominate.

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Reliability Study of the Liquid Target Chamber for <sup>18</sup>F Production at the BATAN’s Cyclotron Facilities

Cited by 4 publications

References 6 publications

Spectral Comparison of Neutron-Irradiated Natural and Enriched Ytterbium Targets for Lu-177 Production

Spectral Comparison of Neutron-Irradiated Natural and Enriched Ytterbium Targets for Lu-177 Production

Identification and Angular Distribution of Residual Radionuclides Detected on the Wall of BATAN’s Cyclotron Cave

Theoretical study on production of stable and radioactive isotopes from proton irradiated sodium chloride

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