Reliability of Field Chromatic Pupillometry for Assessing the Function of Melanopsin-Containing Retinal Ganglion Cells

Zhou, Wu-ying; Lou, Yitian; Pan, Bingxin; Huang, Jinhai

doi:10.1167/iovs.15-16672

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…5,6 By utilising the light sensitivity of the photoreceptors and the characteristic contribution of the rods, cones, and melanopsin to the dynamics of PLR, researchers have used chromatic pupillometry to differentiate the function of these photoreceptors. 4,[9][10][11][12] Pupillometric studies have shown reduced function of ipRGCs in various diseases, including retinitis pigmentosa, glaucoma, and non-arteritic anterior ischaemic optic neuropathy (NAION). [13][14][15][16] Recently, Park et al reported abnormal rodand melanopsin-mediated PLR in IIH patients.…”

Section: Introductionmentioning

confidence: 99%

The Melanopsin-Mediated Pupillary Light Response Is Not Changed in Patients with Newly Diagnosed Idiopathic Intracranial Hypertension

Ba‐Ali

Jensen

Larsen

et al. 2017

Neuro-Ophthalmology

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Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of IIH. In the current study, the authors aimed to measure the PLR in 13 treatment-naive patients with new-onset IIH and 13 healthy controls. In contrast to the previous report, which was based on patients with longstanding IIH ( = 13), the authors found no significant difference in the melanopsin-mediated PLR ( = 0.48).

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