Reliability of Cytologic Smear in Diagnosis of Oral Cancer: A Controlled Study

Shklar, Gerald; Cataldo, E; Meyer, Irving

doi:10.1001/archotol.1970.00770040228010

Cited by 21 publications

(12 citation statements)

References 5 publications

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“…6,8,9 Cytological studies may be useful as a screening tool for the assessment of cellular changes in apparently normal mucosa, in which case a biopsy is not indicated. 6,8,9 Cytological studies may be useful as a screening tool for the assessment of cellular changes in apparently normal mucosa, in which case a biopsy is not indicated.…”

Section: Discussionmentioning

confidence: 99%

“…2 For ethical reasons, these studies used material from necropsy 3 or animals. [5][6][7][8][9] However, studies using the Papanicolaou & Traut classification system have not reported significant results to recommend this method as a tool for early detection of precursor lesions in oral mucosal cells of individuals at risk of squamous cell carcinoma. [5][6][7][8][9] However, studies using the Papanicolaou & Traut classification system have not reported significant results to recommend this method as a tool for early detection of precursor lesions in oral mucosal cells of individuals at risk of squamous cell carcinoma.…”

Section: Introductionmentioning

confidence: 99%

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Exposure to alcohol or tobacco affects the pattern of maturation in oral mucosal cells: a cytohistological study

et al. 2007

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Exposure to alcohol or tobacco affects the pattern of maturation in oral mucosal cells: a cytohistological study

et al. 2007

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“…A number of authors have suggested reasons for this including: inadequate sampling, technical error, misinterpretation of the findings and bias5.13.14. [16][17][18]. It is important that techniques are developed to aid in the diagnosis of early oral cancer especially in predicting the behaviour of those lesions which display epithelial dysplasia but no overt malignancy.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Exfoliative Cytology of Abnormal Oral Mucosal Smears

1988

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SummaryIn this study quantitative techniques have been applied to smears collected from the buccal mucosa and floor of the mouth. The results display an encouraging success rate for identifying premalignant and malignant lesions. 'Intrapatient' normal smears provide a satisfactory control for comparison with pathological smears. Early results indicate that quantitative cytology could be of great value for monitoring and follow-up of suspicious lesions and provide an excellent additional diagnostic test for detecting early oral malignancy.

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“…A positive result is defined as definitive cellular evidence of epithelial dysplasia or carcinoma and atypical result is defined as abnormal epithelial changes of uncertain diagnostic significance (Maraki, Becker, and Boecking 2004). Studies from 1950 to 1970s reported high false negative results for exfoliative cytology (Folsom et al 1972;Shklar, Cataldo, and Meyer 1970;Rovin 1967). For example Folsom et all reported 37% false negative result in 148 oral lesions (Folsom et al 1972).…”

Section: Oral Exfoliative Cytologymentioning

confidence: 99%