“…While the technical literature contains numerous detailed examples of 3D algorithms for reducing speckle and improving image quality, [8][9][10][11] there is relatively little information available on the commercial image processing techniques employed in practice, such as Speckle Reduction Imaging (GE Healthcare, Milwaukee, WI), Xtreme Resolution (Philips Healthcare, Bothell, WA) and, indeed, the meth-ods evaluated in this paper (GOPView and GOPiCE). 6,7,[12][13][14] Currently, the use of such techniques seems to be more of a preference issue for individual physicians rather than established clinical practice. The reliance on proprietary information in commercial image processing techniques makes it very difficult for clinicians to assess the merits of one method over the other, especially as these algorithms are implemented on different scanners, which would confound comparative results even further.…”