Reliability and validity of the Medication Adherence Rating Scale in a cohort of patients with schizophrenia from Nigeria

Owie, Godspower O.; Olotu, Sunday Osasu; James, Bawo Onesirosan

doi:10.1590/2237-6089-2017-0077

Cited by 28 publications

(28 citation statements)

References 22 publications

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“…13 The MARS covers three key aspects: behaviour towards medication adherence (items 1-4), attitude toward taking medication (items 5-8) and negative side effects (items 9 and 10). 14 Each question has a yes or no response. For questions 1-6 and 9-10, a "no" response is suggestive of compliance and given a score of 1.…”

Section: Measurementsmentioning

confidence: 99%

Non-adherence to medications among patients with mental disorders attending tertiary care in Oman

Maqbali¹,

Almashrafi²,

Al-Risi³

et al. 2022

Int J Community Med Public Health

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Background: The primary aim of this study was to quantify the degree of non-adherence to medications among patients with mental health disorders attending a psychiatry clinic at a tertiary care hospital in Muscat, Oman.Methods: All patients attending the psychiatry clinic during the study period were invited to participate in this cross-sectional study. Demographic data and factors related to medication adherence were gathered from the participants. The level of adherence to medication was measured using the Medication Adherence Rating Scale (MARS).Results: A total of 251 patients were included in this study. The average MARS score was 5.7, indicating an overall poor level of compliance. Having an educational level of secondary school, a diagnosis of schizophrenia, having had a mental health condition for a longer time, previous history of admission to a psychiatry unit, lack of insight and poor therapeutic alliance were found to be significantly association with low level of adherence to psychiatric medications.Conclusions: Non-adherence to medications is common among patients with mental health disorders. In order to mitigate the impact of medication non-adherence in a psychiatric setting, appropriate interventions are recommended to address and manage the factors related to poor medication adherence.

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Section: Measurementsmentioning

confidence: 99%

Non-adherence to medications among patients with mental disorders attending tertiary care in Oman

Maqbali¹,

Almashrafi²,

Al-Risi³

et al. 2022

Int J Community Med Public Health

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“…It also consists of questions asking adherence and drug attitude, and the total score is the sum of these questions which is believed to measure adherence in a better quality [22,23]. Furthermore, we have preferred MARS over other screening tools because of its high reliability (Cronbach alpha � 0.76) and high internal consistency (α � 0.80) reported by previous study [24]. Patients who scored below 7 were considered as nonadherent to their antiepileptic medications [25].…”

Section: Outcome Variablementioning

confidence: 99%

Nonadherence to Antiepileptic Medications and Its Determinants among Epileptic Patients at the University of Gondar Referral Hospital, Gondar, Ethiopia, 2019: An Institutional-Based Cross-Sectional Study

Tilahun

Habte

Mekonnen

et al. 2020

Neurology Research International

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Introduction. Nonadherence to antiepileptic medication is the extent of a patient’s passive failure to follow the prescribed therapeutic regimen. The prevalence and impact of nonadherence to antiepileptic medication are high globally. The main purpose of this study was to assess nonadherence to antiepileptic medications and its associated factors among epileptic patients at the University of Gondar Referral Hospital, Gondar, Ethiopia, 2019. Methods. An institutional-based cross-sectional study was conducted among 365 epileptic patients at the University of Gondar Referral Hospital, who were selected by a systematic random sampling technique. Data were collected by face to face interviews using a structured pretested questionnaire. Data were entered into EPI Info version 7 and then exported to SPSS version 22 for analysis. The data were described by descriptive statistics. Binary logistic regression analysis was used as a model, and variables with a p value of less than 0.05 were considered as statistically significant with nonadherence to antiepileptic medications. Results. A total of 356 epileptic patients participated in the study yielding a response rate of 97.5%. The overall prevalence of nonadherence to antiepileptic medications among epileptic patients attending at the University of Gondar Referral Hospital was 38.5% (95% CI: 33.1–43.8). Divorced and/or widowed marital status (AOR: 3.38 (95% CI: 1.54, 7.44)), treatment duration of 3–5 years (AOR = 3.58 (95% CI: 1.38, 9.29)), treatment duration of 5 and above years (AOR: 3.49 (95% CI: 1.53, 7.95)), comorbidity (AOR: 2.42 (95% CI: 1.08, 5.43)), side effects of antiepileptic medications (AOR: 3.36 (95% CI: 1.67, 6.74)), absence of health information (AOR: 1.98 (95% CI: 1.11, 3.52)), epilepsy-related stigma (AOR: 2.81 (95% CI: 1.57, 5.02)), and negative attitude towards antiepileptic medications (AOR: 2.46 (95% CI: 1.36, 4.45)) were significantly associated with nonadherence to antiepileptic medications. Conclusions. Prevalence of nonadherence to antiepileptic medications among epileptic patients at the University of Gondar Referral Hospital was found to be high. Hence, giving health information about epilepsy and its management will help to reduce antiepileptic medications’ nonadherence.

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“…Scores are treated as a continuous measure and a higher score indicates a greater compliance. The MARS demonstrated fair psychometric properties in a previous study ( Owie et al, 2018 ). Therefore, it was selected as one of the standards in this study.…”

Section: Research Instrumentsmentioning

confidence: 65%

Concurrent validity of the Arabic version of General Medication Adherence Scale using two validated indirect adherences measures in Saudi patients with non-communicable diseases

Islam

Nisa

Almuzel

et al. 2021

Saudi Pharmaceutical Journal

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Purpose This study aimed to evaluate the concurrent validity of the Arabic version of the General Medication Adherence Scale (GMAS) using two validated scales namely Adherence to Refills and Medications Scale (ARMS) and Medication Adherence Rating Scale (MARS) in Saudi patients with non-communicable diseases. Methods A cross sectional study was conducted for 2 months in out-patient departments at a tertiary care hospital in Khobar, Saudi Arabia. The study collected data from patients with chronic illnesses through convenience sampling. Pearson correlation (ρ) was conducted to report concurrent validity of GMAS. A correlation coefficient value ≥ 0.5 with p-value < 0.01 was considered threshold for establishing concurrent validity. The study was approved by an ethics committee (IRB-2019–05-002). Results A total of 406 patients responded to the study. The average age was 42.4 ± 5.94 years, and most patients were females (53.7%), married (70%), graduates (65.3%), employed (39.9%) and, had a monthly family income > SAR 10,000, i.e., USD 2666.2 (56.4%). The mean adherence scores obtained from MARS, ARMS and GMAS were 7.09, 19.9, and 27.4. The correlation (ρ) between GMAS and MARS scores was 0.65, and between GMAS and ARMS scores was −0.79, p < 0.01 for both comparisons. Conclusion The concurrent validity of GMAS-AR was established in this study that would further substantiate psychometric properties of the scale in this population.

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Reliability and validity of the Medication Adherence Rating Scale in a cohort of patients with schizophrenia from Nigeria

Cited by 28 publications

References 22 publications

Non-adherence to medications among patients with mental disorders attending tertiary care in Oman

Non-adherence to medications among patients with mental disorders attending tertiary care in Oman

Nonadherence to Antiepileptic Medications and Its Determinants among Epileptic Patients at the University of Gondar Referral Hospital, Gondar, Ethiopia, 2019: An Institutional-Based Cross-Sectional Study

Concurrent validity of the Arabic version of General Medication Adherence Scale using two validated indirect adherences measures in Saudi patients with non-communicable diseases

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