Reliability and Accuracy in Reporting CIN in 14 Laboratories

Branca, Margherita; Morosini, Pierluigi; Duca, Piergiorgio; Verderio, Paolo; Giovagnoli, Maria Rosaria; Riti, Maria Gabriella; Leoncini, Luciano

doi:10.1159/000332170

Cited by 9 publications

(2 citation statements)

References 5 publications

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“…It is also mandatory to systematically monitor the quality of all these procedures and set standards for all of the health professionals involved. Internal quality procedures should be a priority, and an external audit on the QC and QA measures of the laboratory is also required [59,60]. Training personnel is fundamental to maintain high-quality skills and experienced and preferentially certified professionals in continuous education programmes.…”

Section: Discussionmentioning

confidence: 99%

Recommendations on Quality Control and Quality Assurance in Cervical Cytology

Branca

Longatto‐Filho²

2015

Acta Cytologica

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Objective: We aimed to critically evaluate the importance of quality control (QC) and quality assurance (QA) strategies in the routine work of uterine cervix cytology. Study Design: We revised all the main principles of QC and QA that are already being implemented worldwide and then discussed the positive aspects and limitations of these as well as proposing alternatives when pertinent. Results: A literature review was introduced after highlighting the main historical revisions, and then a critical evaluation of the principal innovations in screening programmes was conducted, with recommendations being postulated. Conclusions: Based on the analysed data, QC and QA are two essential arms that support the quality of a screening programme.

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Section: Discussionmentioning

confidence: 99%

Recommendations on Quality Control and Quality Assurance in Cervical Cytology

Branca

Longatto‐Filho²

2015

Acta Cytologica

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“…However, the evaluation of the performance of different laboratories can only be achieved through external quality control [10]. …”

Section: Introductionmentioning

confidence: 99%

External Quality Control of Cervical Cytopathology: Interlaboratory Variability

Ázara¹,

Manrique²,

Souza³

et al. 2013

Acta Cytologica

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Objective: To compare the variability of screening tests held at laboratories with the Unit for External Quality Control (UEQC), checking the frequency of cases that were discordant, false-positive, false-negative, unsatisfactory or that had a delay in clinical management and diagnostic agreement. Materials and Methods: The study analyzed 10,053 screening tests from January 2007 to December 2008, including all positive cases, all those that fall under unsatisfactory and at least 10% of negative screening tests. The magnitude of the agreement was analyzed using the kappa coefficient. Results: Out of the 10,053 cases analyzed, 7.59% were considered disagreeing, and it was estimated that 1.1% were false-negative. There was a delay in the clinical procedure regarding 2.44% cases. There were 2.82% of cases identified as false-positive and 1.24% as unsatisfactory. The diagnostic agreement was excellent (kappa = 0.81). The agreement of most laboratories concerning screening tests was classified as very good. The agreement of the sample adequacy was reasonable (kappa = 0.30) and the agreement regarding the representation of epithelia was considered excellent. Conclusion: Most laboratories showed very good agreement; however, it is worthy of note that to establish the standardization of diagnostic criteria, and enhance the accuracy of screening and improve the quality of cytopathology test results, it is necessary to perform external quality control.

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