Relevant Plasma Parameters for Certification

Gerling, Torsten; Helmke, Andreas; Weltmann, Klaus‐Dieter

doi:10.1007/978-3-319-67627-2_3

Cited by 6 publications

(6 citation statements)

References 120 publications

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“…That for argon spans from 600 to 900 nm, with light emitted by the discharge of electrons primarily visible at 696 nm, 763 nm, and 810 nm (Fig. 2-4) [18,19].…”

Section: Resultsmentioning

confidence: 99%

New Concept of Plasma-Forming : PLASMA Physics for Your Skin Treatment

Choi

2020

Korean Association For Laser Dernatology And Trichology

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The elements that form the Earth appear in the form of solids, liquids, and gases, transitioning between states thereof with changes in temperature. When there is more energy applied to these three basic state, it becomes the plasma. A plasma is formed when there are equal amounts of ionized particles and electrons, called a quasi-neutral state. Plasma with various properties is used in various applied sciences, industries, and medical fields. When artificially generated plasma is used for industrial or medical use, it can be divided into high temperature or thermal plasma and cold plasma according to the temperature. High-temperature plasma is mainly used for industrial purposes such as nuclear fusion, incineration, and metal cutting, whereas low-temperature plasma is used for light-emitting sources, medical fields, and equipment. The most typical characteristic of plasma is the radicals that are generated in various ways. the radicals generated by plasmas are thought to be more effective in killing cancer cells or sterilizing bacteria. Various radicals generated in the plasma destroy the cell wall of bacteria and have a strong sterilizing effect and interestingly, living tissues are hardly damaged under the same conditions. Therefore, plasma has a very good effect on bacterial-infected tissues, thereby can speed up the wound healing process. In particular, interest in plasma for dermatological treatment is increasing, and cases of use for wound healing have been reported in the UK and Germany. In addition, recently, cases of use in acne, athlete's foot, freckles, and atopy have been continuously reported, and as interest in plasma has increased, efforts to apply it to various skin treatments are increasing. Plasma will continue to be actively researched in more fields in the future. Through such efforts, it will be necessary to develop purpose-built plasma generating devices that are easier and more convenient to use. Furthermore, additional research is needed to determine how unstable plasma energy can be accurately adjusted and to develop quantitative methods with which to measure radicals present in a plasma.

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“…That for argon spans from 600 to 900 nm, with light emitted by the discharge of electrons primarily visible at 696 nm, 763 nm, and 810 nm (Fig. 2-4) [18,19].…”

Section: Resultsmentioning

confidence: 99%

New Concept of Plasma-Forming : PLASMA Physics for Your Skin Treatment

Choi

2020

Korean Association For Laser Dernatology And Trichology

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“…A further quartz plate shielded the fluorescent dye from the mechanical gas flow. The spectral sensitivity of the dye in combination with the covering quartz plate was in the range of 200 nm to 370 nm, hence allowing the OH (at approximately 310 nm) and N 2 (spectral range from 300 nm up to 410 nm) irradiation to pass through [4,28]. For VUV irradiation detection, a glass plate was sedimented without binder with a different fluorescent dye (Zn 2 SiO 4 :Mn).…”

Section: Ultraviolet (Uv) and Vacuum Ultraviolet (Vuv) Irradiation Prmentioning

confidence: 99%

“…The The kINPen ® MED (neoplas tools GmbH, Greifswald, Germany) is a cold atmospheric-pressure plasma (CAP) jet which is CE-certified as a medical device, class IIa [1,2]. The generated CAP is an excited and conductive gas state with low temperature (<40 • C) which emits electromagnetic radiation, like ultraviolet, visible and infrared radiation, and other electromagnetic fields and generates charged particles and reactive species [3][4][5]. The most important species-in particular for the antimicrobial efficacy of CAP-are reactive oxygen (ROS) and nitrogen species (RNS) [6,7].…”

Section: Introductionmentioning

confidence: 99%

Concept for Improved Handling Ensures Effective Contactless Plasma Treatment of Patients with kINPen® MED

et al. 2020

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The nursing of patients with wounds is an essential part of medical healthcare. In this context, cold atmospheric-pressure plasma sources can be applied for skin decontamination and stimulation of wound healing. One of these plasma devices is the commercially available kINPen® MED (neoplas tools GmbH), a cold atmospheric-pressure plasma jet which is approved as a medical device, class-IIa. For the plasma treatment, a sterile disposable spacer is recommended to ensure a constant and effective distance between plasma and skin. The disadvantage of this spacer is its form and size which means that the effective axis/area is not visible for the attending doctor or qualified personnel and consequently it is a more or less intuitive treatment. In addition, the suggested perpendicular treatment is not applicable for the attending specialist due to lack of space or patient/wound positioning. A concept of a sensory unit was developed to measure the treatment distance and to visualize the effective treatment area for different angles. To determine the effective area for the plasma treatment, some exemplary methods were performed. Thus, the antimicrobial (Staphylococcus aureus DSM799/ATCC6538) efficacy, reactive oxygen species (ROS) distribution and (vacuum) ultraviolet ((V)UV) irradiation were determined depending on the treatment angle. Finally, a simplified first approach to visualize the effective treatment area at an optimal distance was designed and constructed to train attending specialists for optimal wound area coverage.

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“…CAP is a partially ionized gas that consists of charged and neutral molecules, electromagnetic fields, free reactive molecules and is capable of emitting radiation in visible and ultraviolet range ( 3 ). CAP, also termed non-thermal plasma, operates at temperatures tolerated well by mammalian tissue.…”

Section: Introductionmentioning

confidence: 99%

Argon cold atmospheric plasma eradicates pathogens in vitro that are commonly associated with canine bacterial keratitis

Marx,

Oltmanns,

Meißner

et al. 2024

Front. Vet. Sci.

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PurposeTo investigate the antimicrobial effect of cold atmospheric plasma (CAP) on pathogens associated with canine bacterial keratitis.Materials and methodsPseudomonas aeruginosa, Staphylococcus pseudintermedius, and Streptococcus canis strains, which were obtained from dogs with infectious keratitis, were subjected to testing. For each species, four isolates and a reference strain were cultivated on Columbia sheep blood agar and treated with the kiNPen Vet® plasma pen from Neoplas GmbH, Greifswald, Germany. Various continuous treatment durations (0.5, 2, and 5 min) were applied, along with a 0.5-min treatment repeated four times at short intervals. These treatments were conducted at distances of 3 and 18 mm between the agar surface and the pen.ResultsCAP treatment reduced bacterial growth in all three species. The most effective treatment duration was 5 min at 3 mm distance, resulting in inhibition zones ranging from 19 to 22 mm for P. aeruginosa, 26–45 mm for S. pseudintermedius and an overall reduction of bacterial growth for Str. canis. Inhibition zones were smaller with decreasing treatment duration and larger distance. Treatment times of 30 s repeated four times and 2 min showed comparable results. Treatment with argon alone did not lead to visible reduction of bacterial growth.ConclusionArgon cold atmospheric plasma demonstrated a potent in vitro antimicrobial effect on P. aeruginosa, S. pseudintermedius and Str. canis strains with the latter showing the highest sensitivity.

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Relevant Plasma Parameters for Certification

Cited by 6 publications

References 120 publications

New Concept of Plasma-Forming : PLASMA Physics for Your Skin Treatment

New Concept of Plasma-Forming : PLASMA Physics for Your Skin Treatment

Concept for Improved Handling Ensures Effective Contactless Plasma Treatment of Patients with kINPen® MED

Argon cold atmospheric plasma eradicates pathogens in vitro that are commonly associated with canine bacterial keratitis

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