Relevance of Five-Factor Model personality traits for obsessive–compulsive symptoms in patients with psychotic disorders and their un-affected siblings

Schirmbeck, Frederike; Boyette, Lindy‐Lou; Valk, Renate van der; Meijer, Carin J.; Dingemans, Peter; Van, Rien; Haan, Lieuwe de; Kahn, René S.; Os, Jim van; Wiersma, Durk; Bruggeman, Richard; Cahn, Wiepke; Myin-Germeys, Inez

doi:10.1016/j.psychres.2014.11.066

Cited by 14 publications

(23 citation statements)

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“…Increased sensitivity to stress, negative affectivity and dysfunctional coping have, for example, been shown to constitute key components underlying both symptoms of OCD [ 55 , 56 ] and psychosis [ 57 , 58 ]. Recent investigations suggest that these mechanisms might also be crucial determinants of their co-occurrence [ 7 , 59 ]. As briefly mentioned above, pre-existing higher emotional distress in the two de novo groups could possibly mirror heightened levels of anxiety and stress sensitivity.…”

Section: Discussionmentioning

confidence: 99%

Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings

Schirmbeck

Swets

Meijer

et al. 2016

Eur Arch Psychiatry Clin Neurosci

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The course of obsessive–compulsive symptoms (OCS) and its association with alterations in other clinical variables in patients with psychotic disorders is insufficiently known. Patients (n = 602) and unaffected siblings (n = 652) from the Dutch Genetic Risk and Outcome of Psychosis (GROUP) study were investigated at baseline and after 3 years. Participants were assigned to four groups based on the course of OCS over time: no-OCS, persistent OCS, initial OCS and de novo OCS. In addition to cross-sectional comparisons, longitudinal associations between changes in OCS and symptoms of schizophrenia and general functioning were investigated. Patients with co-occurring OCS reported significantly higher severity of psychotic and affective symptoms as well as lower overall functioning compared to patients without OCS. These differences were stable over time for patients reporting persistent OCS. Subsequent repeated measure analysis revealed significant interaction effects for groups reporting changes in their OCS. Whereas the group with remission of initial OCS showed significant improvement in positive symptoms, emotional distress and functioning, the de novo group showed no significant change in these variables, but rather reported stable higher psychopathology. Similar results were found on a subclinical level in siblings. Patients with co-occurring OCS present a more severe clinical picture, especially if symptoms persist over time. The remission of OCS was associated with overall improvement, whereas individuals with de novo OCS already reported higher clinical impairment before OCS onset. More research is needed to elucidate causal pathways and to develop effective interventions for persistent comorbid OCS.Electronic supplementary materialThe online version of this article (doi:10.1007/s00406-016-0751-0) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings

Schirmbeck

Swets

Meijer

et al. 2016

Eur Arch Psychiatry Clin Neurosci

Self Cite

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“…Reports from the GROUP study represent examples of the prior approach [16 & ,17,18 && ,19], while qualitative studies focusing on patient perspectives [14 & ] and interventions described as individual resiliency training [11 && ] follow the latter approach. Secondly, numerous researchers focused on 'at-risk but resilient' groups including ARMS nonconverters [4 & ] and nonpsychotic siblings of patients with schizophrenia [6 && ,7 && , 8,17,19], in attempts to identify common and distinct properties in comparison to patient groups. Thirdly, several studies used psychological scales to quantify resilience, albeit with differing instruments, and assessed correlations with other clinical variables including psychopathology [10,12,13,21,22 && ].…”

Section: Resultsmentioning

confidence: 99%

“…The authors discuss high self-esteem as a protective factor associated with stigma resilience, and suggest self-esteem as an important target for stigma intervention programs. Schirmbeck et al [27] assessed personality traits using the NEO Five-Factor Inventory (NEO-FFI) to investigate their association with the liability for obsessive compulsive symptoms (OCS) [17]. In this study, patients with nonaffective psychotic disorders and co-morbid OCS showed significantly higher neuroticism and lower extraversion and conscientiousness compared to patients without OCS.…”

Section: Psychological Studiesmentioning

confidence: 94%

Resilience research in schizophrenia

Mizuno

Wartelsteiner

Frajo-Apor

2016

Current Opinion in Psychiatry

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“…The vulnerability hypothesis suggests that personality traits contribute to a general vulnerability, increasing the likelihood of experiencing multiple psychological dis- orders. Additionally, the pathoplasty model proposes that personality factors influence the course and severity of psychological trauma, although they do not establish a causal relationship [ 48 ]. Personality traits have an impact on our perception of events, the environment, and individuals' subjective experience of pain [ 49 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Psychiatric Disorders among Patients with Granulomatosis with Polyangiitis (Wegener's) and the Predictive Role of Personality Traits

Mousavi,

Molaei,

Alesaeidi

et al. 2024

CPEMH

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Background Wegener’s disease is an autoimmune condition affecting the respiratory tract and kidneys. Mental health assessment is crucial due to the impact of psychological disorders on the immune system. Despite this, there is limited community-based research on psychiatric disorders and personality traits among patients with Wegener's disease. Objective This study aimed to investigate the prevalence of psychiatric disorders and examine the predictive role of personality traits among patients with Wegener's disease. Methods A total of 100 patients met the inclusion and exclusion criteria, and all of them were selected to participate in the study. Out of them, 75 individuals completed the questionnaires. The instruments included the SCL-90 questionnaire and the NEO Big Five personality traits. The data were analysed using Stata software, and the prevalence of psychiatric disorders in different patient groups was determined using the chi-square method. The predictive role of personality traits in mental disorders was examined using multivariate regression. Results The results revealed that paranoia (53.3%) and depression (44%) had the highest prevalence in terms of psychiatric disorders, while psychosis (17.3%) and hostility (25.33%) had the lowest prevalence. Additionally, the findings demonstrated a positive correlation between most psychiatric disorders and the neuroticism personality trait. Conclusion Given the influence of mental disorders on the immune system in Wegener's disease, it is essential to provide psychological care for these patients.

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Relevance of Five-Factor Model personality traits for obsessive–compulsive symptoms in patients with psychotic disorders and their un-affected siblings

Cited by 14 publications

References 62 publications

Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings

Obsessive–compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings

Resilience research in schizophrenia

Prevalence of Psychiatric Disorders among Patients with Granulomatosis with Polyangiitis (Wegener's) and the Predictive Role of Personality Traits

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