Release oscillation in a hollow fiber – Part 2: The effect of its frequency on ions release and experimental verification

Li, Gang; Li, Huigai; Liu, Yanping

doi:10.1177/1461348419874973

Cited by 9 publications

(4 citation statements)

References 24 publications

(29 reference statements)

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“…Interestingly, the antimicrobial activity of AgNPs showed long-lasting protection against bacteria compared with povidone iodine. The remaining inhibition zone of the AgNP gel after 48 h could be caused by the action of Ag ions released from AgNPs [ 55 , 56 ]. Ag ions can be released in increments, depending on the oxidation of AgNPs by oxygen, antibacterial substances, chloride and peroxide.…”

Section: Discussionmentioning

confidence: 99%

A Biological Study of Anisotropic Silver Nanoparticles and Their Antimicrobial Application for Topical Use

Thammawithan

Siritongsuk

Nasompag

et al. 2021

Veterinary Sciences

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The excessive use of antibiotics in both human and veterinary medicine has contributed to the development and rapid spread of drug resistance in bacteria. Silver nanoparticles (AgNPs) have become a tool of choice that can be used to treat these resistant bacteria. Several studies have shown that AgNPs have antibacterial and wound healing properties. In this study, we evaluated the biological activity of anisotropic AgNPs to develop an antimicrobial gel formulation for treating wound infections. We showed that some anisotropic AgNPs (S2) have an effective antibacterial activity against bacterial pathogens and low cytotoxicity to keratinocytes and fibroblasts in vitro. The MIC and MBC values were in the range of 2–32 µg/mL, and cytotoxicity had IC50 values of 68.20 ± 9.71 µg/mL and 68.65 ± 10.97 µg/mL against human keratinocyte and normal human dermal fibroblast cells, respectively. The anisotropic AgNPs (S2) were used as a gel component and tested for antibacterial activity, including long-term protection, compared with povidone iodine, a common antiseptic agent. The results show that the anisotropic AgNPs can inhibit the growth of most tested bacterial pathogens and provide protection longer than 48 h, whereas povidone iodine only inhibits the growth of some bacteria. This study suggests that anisotropic AgNPs could be used as an alternative antimicrobial agent for treating bacterial skin infection and as a wound healing formulation.

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Section: Discussionmentioning

confidence: 99%

A Biological Study of Anisotropic Silver Nanoparticles and Their Antimicrobial Application for Topical Use

Thammawithan

Siritongsuk

Nasompag

et al. 2021

Veterinary Sciences

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“…In 1.0 ml of phosphate-buffered saline (PBS) at room temperature, samples of SNM (30 mg) thermo crosslinked with 5% PVA were first swollen for 5 min by shaking (at 100 rpm) ( Lin et al, 2019 ). As soon as the sample reached equilibrium, it was placed in the center of a copper coil.…”

Section: Methodsmentioning

confidence: 99%

An injectable hyperthermic nanofiber mesh with switchable drug release to stimulate chemotherapy potency

Chen

Fujisawa²,

Takanohashi³

et al. 2022

Front. Bioeng. Biotechnol.

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We developed a smart nanofiber mesh (SNM) with anticancer abilities as well as injectability and fast recovery from irregular to non-compressible shapes. The mesh can be injected at the tumor site to modulate and control anticancer effects by loading the chemotherapeutic drug, paclitaxel (PTX), as well as magnetic nanoparticles (MNPs). The storage modulus of the mesh decreases when applied with a certain shear strain, and the mesh can pass through a 14-gauge needle. Moreover, the fibrous morphology is maintained even after injection. In heat-generation measurements, the mesh achieved an effective temperature of mild hyperthermia (41–43°C) within 5 min of exposure to alternating magnetic field (AMF) irradiation. An electrospinning method was employed to fabricate the mesh using a copolymer of N-isopropylacrylamide (NIPAAm) and N-hydroxyethyl acrylamide (HMAAm), whose phase transition temperature was adjusted to a mildly hyperthermic temperature range. Pplyvinyl alcohol (PVA) was also incorporated to add shear-thinning property to the interactions between polymer chains derived from hydrogen bonding, The “on-off” switchable release of PTX from the mesh was detected by the drug release test. Approximately 73% of loaded PTX was released from the mesh after eight cycles, whereas only a tiny amount of PTX was released during the cooling phase. Furthermore, hyperthermia combined with chemotherapy after exposure to an AMF showed significantly reduced cancer cell survival compared to the control group. Subsequent investigations have proven that a new injectable local hyperthermia chemotherapy platform could be developed for cancer treatment using this SNM.

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“…Cell orientation can also be guided by the boundary-induced force induced by adjacent nanofibers. Besides, Lin et al [19,20,49] studied the release oscillation in a hollow fiber and established a fractional model. The results showed that the ions release depends upon the low frequency property.…”

Section: Thermal Oscillation and Its Low Frequency Propertymentioning

confidence: 99%

Thermal Oscillation Arising in a Heat Shock of a Porous Hierarchy and Its Application

Liu¹,

Zhang

et al. 2022

FU Mech Eng

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A building or a bridge might collapse after a heat shock. This paper shows that a porous hierarchy of a coating can effectively prevent a building or a bridge from such damage. A cocoon’s geometrical structure is studied and its resistance to the heat shock is revealed by a thermal oscillator. The theoretical model reveals an extremely low frequency of the thermal oscillator, which is very important for cocoons’ biomechanism, especially in the heat insulation function. At the same time, it shows that the cocoons have the best thickness to protect the pupa from the environment. In addition, surface temperature measurement of hierarchical mulberry leaves is performed. This work provides new insights into biomimetic design of the protective building and coatings.

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Release oscillation in a hollow fiber – Part 2: The effect of its frequency on ions release and experimental verification

Cited by 9 publications

References 24 publications

A Biological Study of Anisotropic Silver Nanoparticles and Their Antimicrobial Application for Topical Use

A Biological Study of Anisotropic Silver Nanoparticles and Their Antimicrobial Application for Topical Use

An injectable hyperthermic nanofiber mesh with switchable drug release to stimulate chemotherapy potency

Thermal Oscillation Arising in a Heat Shock of a Porous Hierarchy and Its Application

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