Release of PEGylated granulocyte-macrophage colony-stimulating factor from chitosan/glycerol films

Films based on chitosan polyelectrolyte complexes for skin drug delivery: Development and characterization

“…This result clearly indicates the formation of the polyelectrolyte complex between chitosan and the PAA in the absence and in the present of additive contents as high as 40%. Another peak detected in all films at approximately 1402 cm −1 is a further evidence of the interaction because it is attributed to the symmetric COO − stretching vibration [15,73,74,76].…”

“…7. This band can be attributed to the overlapping of the peaks due to the asymmetric COO-stretching vibration of PAA and the NH 3 + asymmetric bending vibration of chitosan that are reported in the literature to be located between 1550-1610 cm −1 and 1570-1620 cm −1 , respectively [73,75,76]. This result clearly indicates the formation of the polyelectrolyte complex between chitosan and the PAA in the absence and in the present of additive contents as high as 40%.…”

Hybrid films from blends of chitosan and egg phosphatidylcholine for localized delivery of paclitaxel

“…In this process, the chitosan becomes protonated (NH 3 þ ) and associates with the acetate counter ions. 24 A previous study by Hoffman's group used FTIR to demonstrate that by increasing the amount of glycerol within their chitosan-glycerol film, they were able to displace acetic acid. 24 This was revealed by a shift in the 1560 cm À1 peak, representing the NH 3 þ group in chitosan, from 1560 to 1590 cm…”

Hydrogels for Tissue Engineering and Delivery of Tissue-Inducing Substances

“…84 Delivery of growth factors, plasmids, and adenoviral vectors has also been reported. 84,[108][109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125] In contrast, hyaluronan HGs made by physical preparation only have been less extensively studied due to suboptimal mechanical properties, so that a mild chemical crosslinking step was added at the end of the preparation procedure. 84 However, physical gelation with/in presence of collagen, alginate, polylactide-based microspheres, copper ions, and applied for the restoration of vocal fold lamina propria, cartilage TE, and induction of neovascolarization have been reported.…”